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60352

Sigma-Aldrich

Pyrophosphoric acid

≥95% H4P2O7 basis

Synonym(s):

Diphosphoric acid

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About This Item

Linear Formula:
(HO)2P(O)OP(O)(OH)2
CAS Number:
2466-09-3
Molecular Weight:
177.98
EC Number:
219-574-0
MDL number:
MFCD00011343
UNSPSC Code:
12352106
PubChem Substance ID:
24881848

assay

≥95% H4P2O7 basis

impurities

≤0.001% heavy metals (as Pb)

cation traces

Fe: ≤20 mg/kg
Na: ≤20 mg/kg

SMILES string

OP(O)(=O)OP(O)(O)=O

InChI

1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)

InChI key

XPPKVPWEQAFLFU-UHFFFAOYSA-N

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pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

hcodes

H302,H314

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Florence Mauger et al.
Human mutation, 34(1), 266-273 (2012-11-08)
Here, we describe a high-throughput, single-tube, allele-specific ribonucleotide analog pyrophosphorolysis-activated polymerization (ribo-PAP) PCR multiplex genotyping and resequencing method. An RNA/DNA chimeric PCR product is generated using genomic DNA as starting template, a panel of allele-selective 5'-tagged primers, a reverse primer
Matthew L Fowler et al.
Eukaryotic cell, 11(10), 1249-1256 (2012-08-21)
Acetate kinase (ACK) catalyzes the reversible synthesis of acetyl phosphate by transfer of the γ-phosphate of ATP to acetate. Here we report the first biochemical and kinetic characterization of a eukaryotic ACK, that from the protist Entamoeba histolytica. Our characterization
James E Dunford et al.
Journal of medicinal chemistry, 51(7), 2187-2195 (2008-03-11)
The nitrogen-containing bisphosphonates (N-BPs) are the main drugs currently used to treat diseases characterized by excessive bone resorption. The major molecular target of N-BPs is farnesylpyrophosphate synthase. N-BPs inhibit the enzyme by a mechanism that involves time dependent isomerization of
Megan H Powdrill et al.
Antimicrobial agents and chemotherapy, 54(3), 977-983 (2009-12-24)
We studied the biochemical mechanisms associated with inhibition and resistance to a 4,5-dihydroxypyrimidine carboxylate that inhibits the hepatitis C virus (HCV) RNA-dependent RNA polymerase NS5B. On the basis of the structure of the pharmacophore, it has been suggested that these
Angélica Regina Cappellari et al.
PloS one, 7(10), e47468-e47468 (2012-10-25)
Medulloblastoma (MB) is the most common malignant brain tumor in children and occurs mainly in the cerebellum. Important intracellular signaling molecules, such those present in the Sonic Hedgehog and Wnt pathways, are involved in its development and can also be
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