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453161

Sigma-Aldrich

Manganese(III) 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine chloride tetrakis(methochloride)

Dye content 85 %

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About This Item

Empirical Formula (Hill Notation):
C44H36Cl5MnN8
CAS Number:
125565-45-9
Molecular Weight:
909.01
MDL number:
MFCD00274660
UNSPSC Code:
12352103
PubChem Substance ID:
329756640
NACRES:
NA.23

form

solid

composition

Dye content, 85%

mp

>300 °C (lit.)

λmax

462 nm

SMILES string

CCl.CCl.CCl.CCl.Cl[Mn]1n2c3ccc2c(-c4ccncc4)c5ccc(n5)c(-c6ccncc6)c7ccc(c(-c8ccncc8)c9ccc(n9)c3-c%10ccncc%10)n17

InChI

1S/C40H24N8.4CH3Cl.ClH.Mn/c1-2-30-38(26-11-19-42-20-12-26)32-5-6-34(47-32)40(28-15-23-44-24-16-28)36-8-7-35(48-36)39(27-13-21-43-22-14-27)33-4-3-31(46-33)37(29(1)45-30)25-9-17-41-18-10-25;4*1-2;;/h1-24H;4*1H3;1H;/q-2;;;;;;+3/p-1/b37-29-,37-31-,38-30-,38-32-,39-33-,39-35-,40-34-,40-36-;;;;;;

InChI key

ZSSLGZVVWLRLKL-ZUMCYRATSA-M

Related Categories

General description

Manganese(III) 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine chloride tetrakis(methochloride) (MnTMPyP )is a mitochondrial superoxide dismutase (SOD) mimetic agent.

Application

MnTMPyP was used as a mitochondrial superoxide dismutase mimetic agent in a study to understand the ability of mitochondrial superoxide anion radicals to mediate glutamate-induced oxidative DNA damage.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Novel high-throughput assay for antioxidant capacity against superoxide anion.
Zhang L, et al.
Journal of Agricultural and Food Chemistry, 57(7), 2661-2667 (2009)
Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease
2. Yang JL, et al.
The Journal of Biological Chemistry, 285(36), 28191-28199 (2010)

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