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447854

Sigma-Aldrich

Diethyl 5-(hydroxymethyl)isophthalate

98%

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About This Item

Linear Formula:
HOCH2C6H3-1,3-(CO2C2H5)2
CAS Number:
Molecular Weight:
252.26
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

98%

form

solid

mp

82-85 °C (lit.)

SMILES string

CCOC(=O)c1cc(CO)cc(c1)C(=O)OCC

InChI

1S/C13H16O5/c1-3-17-12(15)10-5-9(8-14)6-11(7-10)13(16)18-4-2/h5-7,14H,3-4,8H2,1-2H3

InChI key

AMRPMZYDTZVKTP-UHFFFAOYSA-N

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Stefan Raddatz et al.
Nucleic acids research, 30(21), 4793-4802 (2002-11-01)
We report the synthesis of new phosphoramidite building blocks and their use for the modification of oligonucleotides with hydrazides. The reaction of these hydrazide oligonucleotides with active esters and aldehydes is demonstrated for solution conjugation and immobilization. Compared with the
Surface adsorption of polar end-functionalised polystyrenes.
Narrainen AP, et al.
Soft Matter, 2(11), 981-985 (2006)
Hydrophobic derivatives of 5-(hydroxymethyl) isophthalic acid that selectively induce apoptosis in leukemia cells but not in fibroblasts.
Galkin A, et al.
Drug Development Research, 69(4), 185-195 (2008)
Gustav Boije af Gennäs et al.
Journal of medicinal chemistry, 52(13), 3969-3981 (2009-05-15)
Protein kinase C (PKC) is a widely studied molecular target for the treatment of cancer and other diseases. We have approached the issue of modifying PKC function by targeting the C1 domain in the regulatory region of the enzyme. Using

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