279927
(1R,5S)-(+)-2-Oxabicyclo[3.3.0]oct-6-en-3-one
99%
Synonym(s):
(1R,5S)-2-Oxabicyclo[3.3.0]oct-6-en-3-one, (3aS,6aR)-3,3a,6,6a-Tetrahydro-2H-1-oxapentalen-2-one, (3aS,6aR)-3,3a,6,6a-Tetrahydro-2H-cyclopenta[b]furan-2-one
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About This Item
assay
99%
optical activity
[α]20/D +102.5°, c = 1 in methanol
mp
45-48 °C (lit.)
SMILES string
O=C1C[C@H]2C=CC[C@H]2O1
Application
Building block for the synthesis of carbocyclic nucleosides.
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Tetrahedron, 52, 8407-8407 (1996)
Bioorganic & medicinal chemistry, 16(15), 7504-7509 (2008-06-24)
Paraoxonase1 (PON1) is a HDL bound enzyme and many of the anti-atherogenic properties of HDL are attributed to PON1. The enzyme precise mechanism of protective action and its endogenous substrate remain elusive. PON1 hydrolyzes organophosphates, arylesters and lactones, whereas the
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