Skip to Content
MilliporeSigma
All Photos(3)

Documents

123323

Sigma-Aldrich

Quinazoline

99%

Synonym(s):

1,3-Benzodiazine, Benzopyrimidine

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C8H6N2
CAS Number:
253-82-7
Molecular Weight:
130.15
Beilstein/REAXYS Number:
109370
EC Number:
205-965-3
MDL number:
MFCD00006712
UNSPSC Code:
12352100
PubChem Substance ID:
24847559
NACRES:
NA.22

Quality Level

100

assay

99%

form

solid

bp

243 °C (lit.)

mp

46-48 °C (lit.)

solubility

H2O: freely soluble
organic solvents: soluble

SMILES string

c1ccc2ncncc2c1

InChI

1S/C8H6N2/c1-2-4-8-7(3-1)5-9-6-10-8/h1-6H

InChI key

JWVCLYRUEFBMGU-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Quinazolines has applications in medicinal chemistry due to their antibacterial, antifungal, anticonvulsant, anti-inflammatory and antitumor activities. It is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.

Application

Quinazoline was used to study the electrochemical behaviour of quinazoline using modern polarographic and voltammetric methods.

Biochem/physiol Actions

Genotoxicity of quinazoline was established by bacterial SOS Chromotest (Escherichia Coli).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

222.8 °F - closed cup

flash_point_c

106 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Reddy Amala et al.
BioImpacts : BI, 11(1), 15-22 (2021-01-21)
Introduction: Inflammation is the primary response caused due to harmful stimuli which are followed by the increased draining of plasma and immune cells from the body into the site of the injured tissue. A signaling cascade of growth factors and
Hamdoon A Mohammed
Medicinal chemistry (Shariqah (United Arab Emirates)), 16(8), 1044-1057 (2020-02-25)
Suaeda is a halophytic genus belonging to the Amaranthaceae family and can survive in the high salted marsh areas of the world. Suaeda plants can biosynthesize natural substances with powerful antioxidant activity and are considered as a renewable source of
Polarographic and voltammetric determination of quinazoline-the structural unit of anticancer drugs.
Hladikova J, et al.
Sensing in Electroanalysis, 3, 165-175 (2008)
Bruna Possato et al.
Dalton transactions (Cambridge, England : 2003), 46(24), 7926-7938 (2017-06-13)
We report on the investigation of a new series of symmetric trinuclear ruthenium complexes combined with azanaphthalene ligands: [Ru
Kunal Nepali et al.
European journal of medicinal chemistry, 196, 112291-112291 (2020-04-24)
This study reports the design, synthesis and evaluation of a series of histone deacetylase (HDAC) inhibitors containing purine/purine isoster as a capping group and an N-(2-aminophenyl)-benzamide unit. In vitro cytotoxicity studies reveal that benzamide 14 suppressed the growth of triple-negative breast
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service