52777-U
SupelMIP® SPE - Aminoglycosides
bed wt. 50 mg, volume 3 mL, pk of 50
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About This Item
UNSPSC Code:
41115712
NACRES:
NB.21
Recommended Products
material
polypropylene tube
product line
SupelMIP®
composition
bed wt., 50 mg
packaging
pk of 50
technique(s)
solid phase extraction (SPE): suitable
volume
3 mL
General description
The SupelMIP SPE line consist s of highly cross-linked polymers that are engineered to extract a single analyte of interest or a class of structurally related analytes with an extremely high degree of selectivity. This is possible because selectivity is introduced during MIP synthesis in which a template molecule, designed to mimic the analyte, guides the formation of specific cavities or imprints that are sterically and chemically complementary to the analyte(s) of interest.
By careful design of the imprinting site, either by molecular modeling, experimental design, or screening methods, the binding cavities can be engineered to offer multiple interaction points with the analyte(s) of interest. This leads to a stronger interaction between the solid-phase and the analyte(s). As a consequence, harsher wash conditions can be tolerated during SPE methodology resulting in cleaner extracts. Because extraction selectivity is significantly improved, lower background is observed allowing analysts to achieve lower limits of detection.
Visit www.sigma-aldrich.com/supelmip to learn more.
By careful design of the imprinting site, either by molecular modeling, experimental design, or screening methods, the binding cavities can be engineered to offer multiple interaction points with the analyte(s) of interest. This leads to a stronger interaction between the solid-phase and the analyte(s). As a consequence, harsher wash conditions can be tolerated during SPE methodology resulting in cleaner extracts. Because extraction selectivity is significantly improved, lower background is observed allowing analysts to achieve lower limits of detection.
Visit www.sigma-aldrich.com/supelmip to learn more.
Application
Developed for the class-selective extraction of aminoglycoside antibiotics from cell culture, honey, and animal tissue matrices
The aminoglycosides that have been tested include: dihydrostreptomycin, streptomycin, tobramycin, kanamycin, amikacin, gentamicin, neomycin, apramycin, spectinomycin and hygromycin B.
The aminoglycosides that have been tested include: dihydrostreptomycin, streptomycin, tobramycin, kanamycin, amikacin, gentamicin, neomycin, apramycin, spectinomycin and hygromycin B.
Features and Benefits
- Highly selective SPE for trace analysis in complex matrices
- Achieve lower detection limits
- Significant time and cost savings
- Improved MS-compatibility
Legal Information
SupelMIP is a registered trademark of Sigma-Aldrich Co. LLC
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Related Content
SupelMIP SPE is based on molecularly imprinted polymer (MIP) technology. Each SupelMIP phase offers tailor-made selectivity for the extraction of trace analytes in complex matrixes.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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