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46911

Supelco

Deoxynivalenol solution

200 μg/mL in ethyl acetate: methanol (95:5), analytical standard

Synonym(s):

3α,7α,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one, DON, Vomitoxin

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About This Item

Empirical Formula (Hill Notation):
C15H20O6
CAS Number:
51481-10-8
Molecular Weight:
296.32
MDL number:
MFCD09039270
UNSPSC Code:
12164500
PubChem Substance ID:
329757261

grade

analytical standard

packaging

ampule of 1 mL

concentration

200 μg/mL in ethyl acetate: methanol (95:5)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

single component solution

storage temp.

−20°C

SMILES string

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O

InChI

1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1

InChI key

LINOMUASTDIRTM-QGRHZQQGSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

EUH066

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

26.6 °F - closed cup

flash_point_c

-3 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
LB98701
LB96491
LB90945
LB83523
LB78053

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Amal Halawa et al.
Archives of animal nutrition, 67(2), 134-146 (2013-03-26)
Deoxynivalenol (DON) is one of the most important trichothecenes, due to its worldwide distribution and common contamination of animal feed. It mainly affects the gastrointestinal tract and the immune system with a high susceptibility for swine. Lipopolysaccharides (LPS) are endotoxins
Sven Dänicke et al.
Toxicology letters, 220(2), 172-180 (2013-04-23)
The systemic effects of the Fusarium toxin deoxynivalenol (DON) and of bacterial lipopolysaccharides (LPS) were studied in male castrated pigs (40.4 ± 3.7 kg) infused intravenously with either DON or LPS alone (100 μg DON/kg/h, 7.5 μg/LPS/kg/h), or together (100
Brenna M Flannery et al.
Toxicology, 304, 192-198 (2013-01-10)
Consumption of the trichothecene deoxynivalenol (DON) suppresses growth in experimental animals - an adverse effect that was used to establish the tolerable daily intake for this toxin. DON ingestion has been recently found to suppress plasma insulin-like growth factor acid-labile
Christina Cowger et al.
Phytopathology, 103(5), 460-471 (2012-12-21)
Fusarium head blight (FHB) affects whole spikes of small grain plants, yet little is known about how FHB develops following infection, or about the concentration or progression of the mycotoxin deoxynivalenol (DON) in non-grain spike tissues. Fusarium mycotoxin levels in
Joelma Lucioli et al.
Toxicon : official journal of the International Society on Toxinology, 66, 31-36 (2013-02-14)
Trichothecenes induce changes in the intestinal barrier function through decreased expression of cell junction proteins and apoptosis of enterocytes. The mitogen activated protein kinases (MAPK) play an important role in the signaling pathways of cell turnover and differentiation. Using ex
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