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T7029

Sigma-Aldrich

Thionin acetate salt

certified by the Biological Stain Commission

Synonym(s):

3,7-Diamino-5-phenothiazinium acetate, Lauth’s violet

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About This Item

Empirical Formula (Hill Notation):
C12H9N3S · C2H4O2
CAS Number:
78338-22-4
Molecular Weight:
287.34
Colour Index Number:
52000
Beilstein/REAXYS Number:
4345073
MDL number:
MFCD00081194
UNSPSC Code:
12171500
PubChem Substance ID:
24900243

grade

certified by the Biological Stain Commission

composition

Dye content, ≥85%

SMILES string

CC([O-])=O.Nc1ccc2nc3ccc(N)cc3[s+]c2c1

InChI

1S/C12H10N3S.C2H4O2/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;1-2(3)4/h1-6H,13-14H2;1H3,(H,3,4)/q+1;/p-1

InChI key

OWXBIRAFHWASMS-UHFFFAOYSA-M

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Application

For use as a general nuclear stain for chromatin and mucin; for staining Nissl granules by end-point buffering and for showing malignant cells in frozen biopsy sections; and as a stain for semi-thin sections of plant material for light microscopy.

Suitability

Certified for use in Churukian-Schenk thionine method; Stoughton′s method for plant material.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKBS9041V
MKBP7371V
MKBL4848V
MKBG6734V
MKBD0109

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Agustina Cabral et al.
Molecular metabolism, 32, 69-84 (2020-02-08)
Arcuate nucleus (ARC) neurons producing Agouti-related peptide (AgRP) and neuropeptide Y (NPY; ARCAgRP/NPY neurons) are activated under energy-deficit states. ARCAgRP/NPY neurons innervate the hypothalamic paraventricular nucleus (PVH), and ARC→PVH projections are recognized as key regulators of food intake. Plasma ghrelin
Selvaraj Baskar et al.
Biosensors & bioelectronics, 33(1), 95-99 (2012-01-24)
We report here a novel detection scheme for simultaneous detection of NADH and H(2)O(2) based on a bifunctional poly(thionine)-modified electrode. Electropolymerization of thionine on a "preanodized" screen-printed carbon electrode effectively lowers the oxidation potential of NADH to 0.15 V (vs.
Aline Dall'Oglio et al.
The Journal of comparative neurology, 521(3), 589-611 (2012-07-19)
The medial nucleus (Me) is a superficial component of the amygdaloid complex. Here we assessed the density and morphology of the neurons and glial cells, the glial fibrillary acidic protein (GFAP) immunoreactivity, and the ultrastructure of the synaptic sites in
Zhoumin Sun et al.
Analytica chimica acta, 761, 84-91 (2013-01-15)
In this paper, we fabricate a sensitive and stable amperometric UA amperometric biosensor using nanobiocomposite derived from thionine modified graphene oxide in this study. A simple wet-chemical strategy for synthesis of thionine-graphene oxide hybrid nanosheets (T-GOs) through π-π stacking has
Yunying Xie et al.
Analytica chimica acta, 699(1), 44-48 (2011-06-28)
We reported a graphene-based immunosensor for electrochemical quantification of phosphorylated p53 on serine 15 (phospho-p53(15)), a potential biomarker of gamma-radiation exposure. The principle is based on sandwich immunoassay and the resulting immunocomplex is formed among phospho-p53 capture antibody, phospho-p53(15) antigen
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