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S5442

Sigma-Aldrich

SyntheChol® NS0 Supplement

500 ×, synthetic cholesterol, animal component-free, aqueous solution, sterile-filtered, suitable for cell culture

Synonym(s):

Cholesterol solution

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About This Item

Empirical Formula (Hill Notation):
C27H46O
CAS Number:
57-88-5
Molecular Weight:
386.65
MDL number:
MFCD00003646
UNSPSC Code:
12352211
eCl@ss:
39023139
PubChem Substance ID:
24899653
NACRES:
NA.75

biological source

non-animal source

Quality Level

500

sterility

sterile-filtered

product line

BioXtra

form

aqueous solution

concentration

500 ×

technique(s)

cell culture | mammalian: suitable

storage temp.

2-8°C

SMILES string

[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])[C@H](C)CCCC(C)C

InChI

1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChI key

HVYWMOMLDIMFJA-DPAQBDIFSA-N

Gene Information

human ... POLA1(5422) , TOP2A(7153)
rat ... Ar(24208) , Polb(29240)

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Application

SyntheChol® NS0 Supplement is used as media supplement for NS0 mouse myeloma cell growth and the growth of other cholesterol-dependent cell lines.

Features and Benefits

Synthetic, non-animal cholesterol solution that is designed as a supplement to our hybridoma media formulations to promote excellent cell growth and protein productivity for NS0 mouse myeloma and other cholesterol-dependent cell lines.

Legal Information

Sabril is a registered trademark of Lundbeck LLC
SyntheChol is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Arthur Nathan Brodsky et al.
Methods (San Diego, Calif.), 56(3), 408-417 (2011-10-29)
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BMC biotechnology, 9, 70-70 (2009-08-13)
Tumour associated antigens on the surface of tumour cells, such as MUC1, are being used as specific antibody targets for immunotherapy of human malignancies. In order to address the poor penetration of full sized monoclonal antibodies in tumours, intermediate sized
Marco Guadagnoli et al.
Blood, 117(25), 6856-6865 (2011-05-06)
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