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P5681

Sigma-Aldrich

Phytic acid dipotassium salt

Synonym(s):

myo-Inositol hexakis(dihydrogen phosphate), Inositol hexakisphosphate, Inositol hexaphosphoric acid, InsP6

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About This Item

Linear Formula:
C6H16O24P6K2
CAS Number:
129832-03-7
Molecular Weight:
736.22
MDL number:
MFCD00133773
UNSPSC Code:
12352201
PubChem Substance ID:
24898692

storage condition

desiccated

storage temp.

2-8°C

SMILES string

[K].OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O

InChI

1S/C6H18O24P6.K.H/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24);;

InChI key

ZSQQRQRTIJIVNO-UHFFFAOYSA-N

General description

Phytic acid is a major determinant of zinc bioavailability.

Application

Phytic acid has been used in a study to develop a novel method to reduce fishy aftertaste in wine and seafood pairing. It has also been used in a study to investigate biochemical and nutritional characterization of dry and processed seeds.

Biochem/physiol Actions

Phytic acid is present in all eukaryotic cells. In plants, it is known to function as a [PO4]3− storage depot and precursor for other inositol phosphates and pyrophosphates. Its high surface negative charge makes it a potent chelator of divalent and trivalent cations in vitro, and it is most likely associated with Ca2+ or Mg2+ ions in vivo. In yeast, phytic acid acts with the nuclear pore protein Gle1 to regulate the nuclear export of mRNA by coactivating the RNA-dependent ATPase activity of DExD-box protein 5 (Dbp5).

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Angela R Piergiovanni et al.
Journal of the science of food and agriculture, 92(11), 2387-2393 (2012-03-16)
An ecotype of the lima bean, named 'fagiolo a Formella', which, to the best of our knowledge, is the only example of an Italian lima bean (Phaseolus lunatus L.) ecotype, is cultivated in the Campania region of southern Italy. Physical
Bo-Jane Woods et al.
PloS one, 15(11), e0242202-e0242202 (2020-11-12)
Zinc deficiency is a major public health problem in vulnerable populations of Latin America and the Caribbean. Biofortification of rice (Oryza sativa L.) with zinc has the potential to alleviate zinc deficiencies. However, as plant breeding processes can alter grain
Genis Andrés Castillo Villamizar et al.
mBio, 10(1) (2019-01-31)
Phosphatases, including phytases, play a major role in cell metabolism, phosphorus cycle, biotechnology, and pathogenic processes. Nevertheless, their discovery by functional metagenomics is challenging. Here, soil metagenomic libraries were successfully screened for genes encoding phosphatase activity. In this context, we
Darla DeStephanis et al.
Biochemical and biophysical research communications, 460(3), 609-615 (2015-03-25)
The translesion DNA synthesis (TLS) polymerase REV1 is implicated in the bypass of the irreparable DNA damage such as interstrand crosslinks (ICLs). However, the potential role of REV1 in DNA damage response (DDR) pathway has not been determined. In this
Genis Andrés Castillo Villamizar et al.
Genes, 10(2) (2019-02-01)
Protein tyrosine phosphatases (PTPs) fulfil multiple key regulatory functions. Within the group of PTPs, the atypical lipid phosphatases (ALPs) are known for their role as virulence factors associated with human pathogens. Another group of PTPs, which is capable of using
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