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L7007

Sigma-Aldrich

Lysergic acid diethylamide

Synonym(s):

LSD, Lysergide

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About This Item

Empirical Formula (Hill Notation):
C20H25N3O
CAS Number:
50-37-3
Molecular Weight:
323.43
EC Number:
200-033-2
MDL number:
MFCD00135795
UNSPSC Code:
12352106
PubChem Substance ID:
24896390
NACRES:
NA.77

Quality Level

200

drug control

USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

storage temp.

−20°C

SMILES string

[H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34

InChI

1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1

InChI key

VAYOSLLFUXYJDT-RDTXWAMCSA-N

Gene Information

human ... DRD2(1813) , HTR1A(3350) , HTR2A(3356) , HTR2C(3358) , HTR6(3362)
rat ... Htr1a(24473) , Htr2a(29595) , Htr2c(25187) , Htr7(65032)

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Biochem/physiol Actions

Potent hallucinogen; non-selective serotonin receptor agonist.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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H S Swartzwelder et al.
Scientific reports, 9(1), 12110-12110 (2019-08-23)
Adolescent intermittent ethanol (AIE) exposure diminishes neurogenesis and dendritic spine density in the dentate gyrus. The cholinesterase inhibitor, donepezil (Aricept), reverses AIE effects on dendritic spines, possibly by interacting with inflammatory and/or epigenetic mediators after AIE exposure. This study tests
Mauro Murgia et al.
Frontiers in neurology, 9, 348-348 (2018-06-19)
The use of rhythmic auditory stimulation (RAS) has been proven useful in the management of gait disturbances associated with Parkinson's disease (PD). Typically, the RAS consists of metronome or music-based sounds (artificial RAS), while ecological footstep sounds (ecological RAS) have
Ming-Jie Kuang et al.
International journal of biological sciences, 15(9), 1861-1871 (2019-09-17)
Purpose: Glucocorticoid-induced osteonecrosis of the femoral head (GIONFH) is a common disease after long-term or high-dose glucocorticoid use. The pathogenesis of GIONFH is still controversial, and abnormal bone metabolism caused by glucocorticoids may be one of the important factors. Exosomes
Concha Collar et al.
Food science and technology international = Ciencia y tecnologia de los alimentos internacional, 23(1), 24-35 (2016-07-22)
The use of pseudocereals, legumes and ancient grains for breadmaking applications is receiving particular attention since they involve nutrient dense grains with proven health-promoting attributes. Dilution up to 45% of the basic wheat flour matrix by accumulative ternary addition of
Christina Grumann et al.
Journal of pharmaceutical and biomedical analysis, 174, 270-276 (2019-06-11)
A variety of hallucinogens of the lysergamide type has emerged on the drug market in recent years and one such uncontrolled derivative of lysergic acid diethylamide (LSD) is 1-propionyl-LSD (1P-LSD). Due to the high potency of LSD and some of
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