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E8512

Sigma-Aldrich

Ethylmorphine

Synonym(s):

Morphine 3-ethyl ether

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About This Item

Empirical Formula (Hill Notation):
C19H23NO3
CAS Number:
76-58-4
Molecular Weight:
313.39
EC Number:
200-970-7
MDL number:
MFCD00083327
UNSPSC Code:
12352200
PubChem Substance ID:
24894676
NACRES:
NA.77

drug control

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

storage temp.

2-8°C

SMILES string

CCOc1ccc2C[C@@H]3C4C=C[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C

InChI

1S/C19H23NO3/c1-3-22-15-7-4-11-10-13-12-5-6-14(21)18-19(12,8-9-20(13)2)16(11)17(15)23-18/h4-7,12-14,18,21H,3,8-10H2,1-2H3/t12-,13+,14-,18-,19-/m0/s1

InChI key

OGDVEMNWJVYAJL-LEPYJNQMSA-N

Biochem/physiol Actions

Narcotic analgesic; antitussive

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H336

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Aliaa Nabil ElMeshad et al.
AAPS PharmSciTech, 21(7), 244-244 (2020-08-29)
Ethylmorphine hydrochloride (EtM) is a derivative of morphine used as analgesic to treat severe pain in case of cancer and bone injury. This study aimed to formulate and evaluate core in cup tablets containing 2 doses of EtM, the cup
C Popa et al.
Journal of analytical toxicology, 22(2), 142-147 (1998-04-21)
In drugs-of-abuse testing, opiates constitute a delicate and controversial task because morphine may occur in urine for several reasons. Ethylmorphine (EtM), which is used as an antitussive drug in many countries, is metabolically converted to morphine. The present study was
K Hedenmalm et al.
Therapeutic drug monitoring, 19(6), 643-649 (1998-01-08)
The formation of morphine from codeine and ethylmorphine is mainly mediated by the polymorphic enzyme CYP2D6. The objective of this study was to investigate whether CYP2D6 poor metabolizers (PM) and CYP2D6 extensive metabolizers (EM) would respond differently during testing for
Gyula Szucs et al.
Chemico-biological interactions, 147(2), 151-161 (2004-03-12)
Tiamulin, a diterpene antibiotic, is used for treatment of pulmonary and gastrointestinal infections in swine and poultry. Combined administration of tiamulin and ionophores (e.g. monensin) to farm animals may lead to intoxication manifested in severe clinical symptoms. Tiamulin metabolite complex
A Wayne Jones et al.
Journal of analytical toxicology, 32(4), 265-272 (2008-04-24)
Morphine and codeine are frequently identified in blood samples from impaired drivers. But whether these opiates reflect the use of prescription analgesics or abuse of the illicit drug heroin (diacetyl morphine) is not always obvious. Opiates, either alone or together
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