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Key Documents

V0255

Sigma-Aldrich

[pGlu4, (Cys2)6, Arg8]-Vasopressin Fragment 4-9 acetate salt

≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C28H46N12O10S2 · xC2H4O2
CAS Number:
Molecular Weight:
774.87 (free base basis)
MDL number:
UNSPSC Code:
12352200

assay

≥95% (HPLC)

UniProt accession no.

storage temp.

−20°C

SMILES string

CC(O)=O.N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)C(O)=O

Gene Information

human ... AVP(551)

Amino Acid Sequence

pGlu-Asn-Cys(Cys)-Pro-Arg-Gly-NH2

Biochem/physiol Actions

A more potent neuropeptide than AVP with selective effects on memory and related processes.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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J P Burbach et al.
Science (New York, N.Y.), 221(4617), 1310-1312 (1983-09-23)
A peptide that accumulated as the major product during the proteolysis of arginine vasopressin by rat brain synaptic membranes was isolated and its structure was shown to be the hexapeptide pGlu-Asn-Cys(Cys)-Pro-Arg-Gly-NH2. When administered intracerebroventricularly in extremely low doses, this vasopressin

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