All Photos(1)

Key Documents

COO/COA

View All Documentation

T5299

Trifucosyllacto-N-hexaose a

Name: Trifucosyllacto-N-hexaose a
Brand: SIGMA

from human milk, ≥90% (HPLC)

Synonym(s):

TFLNH(a)

Sign Into View Organizational & Contract Pricing

All Photos(1)

About This Item

Empirical Formula (Hill Notation):

C₅₈H₉₈N₂O₄₃

CAS Number:

116883-09-1

Molecular Weight:

1511.39

MDL number:

MFCD00467032

UNSPSC Code:

12352201

PubChem Substance ID:

24900266

biological source

human milk

assay

≥90% (HPLC)

form

solid

storage temp.

−20°C

SMILES string

CC1OC(OC2C(O)C(O)C(CO)OC2OC3C(NC(C)=O)C(OC(CO)C3OC4OC(C)C(O)C(O)C4O)OC5C(O)C(COC6OC(CO)C(OC7OC(CO)C(O)C(O)C7O)C(OC8OC(C)C(O)C(O)C8O)C6NC(C)=O)OC(OC(C(O)CO)C(O)C(O)C=O)C5O)C(O)C(O)C1O

InChI

1S/C58H98N2O43/c1-13-27(71)34(78)39(83)53(89-13)98-46-23(11-66)95-52(26(60-17(5)68)48(46)101-58-50(38(82)32(76)21(9-64)93-58)103-55-41(85)36(80)29(73)15(3)91-55)102-49-33(77)24(96-57(43(49)87)97-44(19(70)7-62)30(74)18(69)6-61)12-88-51-25(59-16(4)67)47(100-54-40(84)35(79)28(72)14(2)90-54)45(22(10-65)94-51)99-56-42(86)37(81)31(75)20(8-63)92-56/h6,13-15,18-58,62-66,69-87H,7-12H2,1-5H3,(H,59,67)(H,60,68)

InChI key

YOTBLRKYLWEPOA-UHFFFAOYSA-N

Other Notes

A natural nonasaccharide containing the Lewis-X substructure.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Structural analysis of underivatized neutral human milk oligosaccharides in the negative ion mode by nano-electrospray MS(n) (part 1: methodology).

Anja Pfenninger et al.

Journal of the American Society for Mass Spectrometry, 13(11), 1331-1340 (2002-11-22)

Underivatized neutral oligosaccharides from human milk were analyzed by nano-electrospray ionization (ESI) using a quadrupole ion trap mass spectrometer (QIT-MS) in the negative-ion mode. Under these conditions neutral oligosaccharides are observed as deprotonated molecules [M-H]- with high intensity. CID-experiments of

Primary structure of human milk nona- and decasaccharides determined by a combination of fast atom bombardment mass spectrometry and 1H-/13C-nuclear magnetic resonance spectroscopy. Evidence for a new core structure, iso-lacto-N-octaose.

G Strecker et al.

Glycoconjugate journal, 6(2), 169-182 (1989-01-01)

The structure of a nonasaccharide and of two decasaccharides isolated from human milk has been investigated by using methylation, fast atom bombardment mass spectrometry and 1H-/13C-nuclear magnetic resonance spectroscopy. The structures of these oligosaccharides were: trifucosyllacto-N-hexaose; Fuc alpha 1-2Gal beta

Inhibition of monocyte, lymphocyte, and neutrophil adhesion to endothelial cells by human milk oligosaccharides.

Lars Bode et al.

Thrombosis and haemostasis, 92(6), 1402-1410 (2004-12-08)

Excessive leukocyte infiltration causes severe tissue damage in a variety of inflammatory diseases. The initial step in leukocyte extravasation is mediated by selectins and oligosaccharides on their glycoconjugate ligands. Human milk is a rich source of lactose-derived oligosaccharides that are

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service