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SIL350

Sigma-Aldrich

Silicic acid

BioReagent, suitable for column chromatography, 100-200 mesh (75 - 150 μm)

Synonym(s):

hydrated silica, metasilcic, silica acid

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100 G
$126.72
1 KG
$746.00

$126.72

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100 G
$126.72
1 KG
$746.00

About This Item

Empirical Formula (Hill Notation):
H2O3Si
CAS Number:
7699-41-4
Molecular Weight:
78.10
EC Number:
231-716-3
MDL number:
MFCD00054122
UNSPSC Code:
23201100
PubChem Substance ID:
24899864
NACRES:
SB.54

$126.72

List price$144.00Save 12%
Web-Only Promotion

Available to ship onApril 08, 2025Details

product line

BioReagent

assay

≥99.8% Si (as SiO2) basis

form

solid

particle size

100-200 mesh (75 - 150 μm)

suitability

suitable for column chromatography

SMILES string

O[Si](O)=O

InChI

1S/H2O3Si/c1-4(2)3/h1-2H

InChI key

IJKVHSBPTUYDLN-UHFFFAOYSA-N

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Application

For general chromatographic use.
Silicic acid has been used as a column material for the purification of polyunsaturated fatty acids,[1] fatty acid methyl ester,[2] nucleic acid extraction from Suillus bovinus[3] and lipid fractionation from soy milk powder.[4]
Silicic acid is used in protein chromatography. Silicic acid has been used in a study to demonstrate the anti-biofilm potential of a glycolipid surfactant produced by a tropical marine strain of Serratia marcescens. Silicic acid has also been used to study the antioxidant activity of fresh and processed Jalapeño and Serrano peppers.

Biochem/physiol Actions

Silicic acid polymers are employed in water treatment systems, drug encapsulation cum delivery and for soluble nanoparticle generation.[5] Silicic acid interacts with aluminum and reduces its bioavailability. It is an effective antidote for aluminum poisoning.[6]

Preparation Note

Acid-washed.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX0585
MKCT3569
MKCQ5197
MKCL0362
MKCC8767

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Silicic acid: its gastrointestinal uptake and urinary excretion in man and effects on aluminium excretion
Reffitt DM, et al.
Journal of Inorganic Biochemistry, 76(2), 141-147 (1999)
Leroy S Pakkiri et al.
Glycobiology, 15(3), 291-302 (2004-10-16)
Based on recent analytical and enzymological studies, a topological model for the role of alpha-D-mannosyl-(1-->3)-alpha-D-mannosyl-(1-->3)-diacylglycerol (Man(2)-DAG) as a lipid anchor precursor and mannosylphosphorylundecaprenol (Man-P-Und) as a mannosyl donor in the assembly of a membrane-associated lipomannan (LM) in Micrococcus luteus has
<I>Suillus bovinus</I> glutamine synthetase gene organization, transcription and enzyme activities in the Scots pine mycorrhizosphere developed on forest humus.
Juuti, J.T., et al.
The New phytologist, 164(2), 389-399 (2004)
Koki Nagayama et al.
The Journal of antimicrobial chemotherapy, 50(6), 889-893 (2002-12-04)
The bactericidal activity of phlorotannins from brown algae against food-borne pathogenic bacteria (25 strains), methicillin-resistant Staphylococcus aureus (MRSA) (nine strains) and Streptococcus pyogenes (one strain) was examined and compared with that of catechins. In addition, the effect of the oral
Characterization of a spray-dried soymilk powder and changes observed during storage
Osthoff G, et al.
Food Science and Technology International = Ciencia y tecnologia de Los Alimentos Internacional, 16(2), 169-178 (2010)
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