S8259
2,2′-Sulfinyl-bis(4,6-dichlorophenol)
Synonym(s):
Bithionol sulfoxide
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SMILES string
Oc1c(Cl)cc(Cl)cc1S(=O)c2cc(Cl)cc(Cl)c2O
InChI
1S/C12H6Cl4O3S/c13-5-1-7(15)11(17)9(3-5)20(19)10-4-6(14)2-8(16)12(10)18/h1-4,17-18H
InChI key
RPAJWWXZIQJVJF-UHFFFAOYSA-N
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Mutation research, 188(1), 53-55 (1987-05-01)
The mutagenic effects of bithionol sulfoxide and its two major metabolites, bithionol and bithionol sulfone, on 4 Salmonella typhimurium strains (TA97, TA98, TA100 and TA102) were investigated. Bithionol sulfoxide was found to be mutagenic to TA98 and TA100. However, mutagenicity
[Experimental and calculated n-octanol/water partition coefficient of bithionol sulfoxide].
Annales pharmaceutiques francaises, 43(2), 165-171 (1985-01-01)
[Ionization constants of bithionol sulfoxide].
Annales pharmaceutiques francaises, 41(5), 473-481 (1983-01-01)
The Journal of toxicological sciences, 6(4), 307-314 (1981-11-01)
The metabolic detoxication of bis(2-hydroxy-3, 5-dichlorophenyl)sulfoxide (BTS) in man was investigated. Bis(2-hydroxy-3, 5-dichlorophenyl)sulfide (BT) was identified in beta-glucuronidase treated urine following the administration of BTS by thin-layer chromatography, gas chromatography, ultraviolet spectrum and quantitative analysis. No other metabolites were detectable.
Veterinarni medicina, 25(9), 557-563 (1980-09-01)
The elimination of the sources of invasion, i. e. hay and forage coming from the infested biotopes, combined with the administration of bithionol sulphoxide, resulted in a reduction of the invasion of cattle by Fascioloides magna from 21.1 to 3.2%
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