S6389

1-Stearoyl-2-arachidonoyl-sn-glycerol

~98%, suitable for stimulation of protein kinase C derived from liver cells, liquid

• Synonym(s): 1-Octadecanoyl-2-([cis,cis,cis,cis]-5,8,11,14-eicosatetraenoyl)-sn-glycerol, 2-Arachidonoyl-1-stearoyl-sn-glycerol
• Empirical Formula (Hill Notation): C₄₁H₇₂O₅
• CAS Number: 65914-84-3
• Molecular Weight: 645.01
• Beilstein/REAXYS Number: 2198923
• MDL number: MFCD00070361
• UNSPSC Code: 41106305
• PubChem Substance ID: 24899699

Properties

• assay: ~98%
• form: liquid
• impurities: 1,3-isomer, trace
• solubility: chloroform: 20 mg/ml
• suitability: suitable for stimulation of protein kinase C derived from liver cells
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC
• InChI: 1S/C41H72O5/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h11,13,17,19,22,24,28,30,39,42H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3/b13-11-,19-17-,24-22-,30-28-
• InChI key: NSXLMTYRMFVYNT-LGHBDAFPSA-N

Description

Application

1-Stearoyl-2-arachidonoyl-sn-glycerol was used to study Ca⁺² signaling.^5,6

Biochem/physiol Actions

1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacyl glycerol (DAG) that allosterically activates PKC and other proteins that affect cell growth, development, survival, apoptosis, carcinogenesis and metastasis.³ It activates transient receptor potential channels 3 and 6 that regulates the intracellular free calcium levels.⁴

Packaging

Sealed ampule

Caution

This material may isomerize during storage.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)