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Key Documents

S5758

Sigma-Aldrich

Sodium tetrathionate dihydrate

≥98% (titration)

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About This Item

Linear Formula:
NaO3SS2SO3Na · 2H2O
CAS Number:
Molecular Weight:
306.27
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

≥98% (titration)

solubility

H2O: 200 + 4mL H2O mg, clear to hazy, colorless to faintly yellow

density

2.1 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

O.O.[Na+].[Na+].[O-]S(=O)(=O)SSS([O-])(=O)=O

InChI

1S/2Na.H2O6S4.2H2O/c;;1-9(2,3)7-8-10(4,5)6;;/h;;(H,1,2,3)(H,4,5,6);2*1H2/q2*+1;;;/p-2

InChI key

HAEPBEMBOAIUPN-UHFFFAOYSA-L

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Application


  • Gaussia princeps luciferase: a bioluminescent substrate for oxidative protein folding.: Sodium tetrathionate dihydrate is used to study its impact on the oxidative folding of proteins, utilizing Gaussia princeps luciferase as a bioluminescent substrate. This study advances understanding of protein chemistry and bioluminescence applications in biochemical assays (Yu T et al., 2018).

  • https://doi.org/10.2174/092986612800190973
    https://doi.org/10.1080/10826068.2011.544230
    https://doi.org/10.11150/kansenshogakuzasshi.83.380
  • A spectroscopic investigation into the reaction of sodium tetrathionate with cysteine.: The research utilizes spectroscopic methods to study the reaction between sodium tetrathionate dihydrate and cysteine, providing insights into the chemical interactions and potential applications in biochemistry and molecular biology (Church JS et al., 2008).

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

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Lars Ole Simonsen et al.
Blood cells, molecules & diseases, 47(4), 214-225 (2011-10-04)
The passive transport of calcium and cobalt and their interference were studied in human red cells using (45)Ca and (57)Co as tracers. In ATP-depleted cells, with the ATP concentration reduced to about 1μM, the progress curve for (45)Ca uptake at
Tadayoshi Kanao et al.
Journal of biotechnology, 132(1), 16-22 (2007-10-02)
Tetrathionate is one of the most important intermediates in dissimilatory sulfur oxidation and can itself be utilized as a sole energy source by some sulfur-oxidizing microorganisms. Tetrathionate hydrolase (4THase) plays a significant role in tetrathionate oxidation and should catalyze the
Carlos R Llerena-Suster et al.
Preparative biochemistry & biotechnology, 41(2), 107-121 (2011-03-29)
Papain from latex of Carica papaya was purified up to matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry homogeneity by salt precipitation from two different crude extract sources: a refined preparation obtained in our laboratory and a commercial one. Sodium
Sebastian E Winter et al.
Nature, 467(7314), 426-429 (2010-09-25)
Salmonella enterica serotype Typhimurium (S. Typhimurium) causes acute gut inflammation by using its virulence factors to invade the intestinal epithelium and survive in mucosal macrophages. The inflammatory response enhances the transmission success of S. Typhimurium by promoting its outgrowth in
Leonardo J van Zyl et al.
Applied and environmental microbiology, 74(18), 5686-5694 (2008-07-29)
Acidithiobacillus caldus is a moderately thermophilic, acidophilic bacterium that has been reported to be the dominant sulfur oxidizer in stirred-tank processes used to treat gold-bearing arsenopyrite ores. It is also widely distributed in heap reactors used for the extraction of

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