S3321

SUN B8155

≥97% (HPLC), solid

• Synonym(s): 5-[1-[(2-Aminophenyl)imino]ethyl]-1,6-dihydroxy-4-methyl-2(1H)-pyridinone
• Empirical Formula (Hill Notation): C₁₄H₁₅N₃O₃
• CAS Number: 345893-91-6
• Molecular Weight: 273.29
• MDL number: MFCD08276926
• UNSPSC Code: 51111800
• PubChem Substance ID: 24724606

Properties

• assay: ≥97% (HPLC)
• form: solid
• solubility: DMSO: ≥5 mg/mL
• storage temp.: 2-8°C
• SMILES string: CC1=CC(=O)N(O)C(O)=C1\C(C)=N\c2ccccc2N
• InChI: 1S/C14H15N3O3/c1-8-7-12(18)17(20)14(19)13(8)9(2)16-11-6-4-3-5-10(11)15/h3-7,19-20H,15H2,1-2H3/b16-9+
• InChI key: SGJLINMLDNLWOS-CXUHLZMHSA-N

Description

Application

SUN B8155 may be used to study calcitonin-mediated cell signaling.

Biochem/physiol Actions

SUN B8155 is a pyridine derivative that mimics calcitonin, a peptide hormone crucial in maintain the bone homeostasis. It stimulated the formation of cAMP in T47D and UMR106-06 cells expressing calcitonin receptor.

SUN B8155 is a nonpeptide calcitonin receptor agonist.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves