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S2275

Sigma-Aldrich

Acetyl-[Arg6, Sar9, Met(O2)11]-Substance P Fragment 6-11

≥95%

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About This Item

Empirical Formula (Hill Notation):
C40H60N10O9S
CAS Number:
121951-71-1
Molecular Weight:
857.03
MDL number:
MFCD00076798
UNSPSC Code:
12352200
PubChem Substance ID:
24899517
NACRES:
NA.32

assay

≥95%

UniProt accession no.

P20366

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)CN(C)C(=O)C(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)C(CCCNC(N)=N)NC(C)=O)C(=O)NC(CCS(C)(=O)=O)C(N)=O

InChI

1S/C40H60N10O9S/c1-25(2)21-31(37(55)47-29(35(41)53)18-20-60(5,58)59)46-34(52)24-50(4)39(57)33(23-28-15-10-7-11-16-28)49-38(56)32(22-27-13-8-6-9-14-27)48-36(54)30(45-26(3)51)17-12-19-44-40(42)43/h6-11,13-16,25,29-33H,12,17-24H2,1-5H3,(H2,41,53)(H,45,51)(H,46,52)(H,47,55)(H,48,54)(H,49,56)(H4,42,43,44)

InChI key

YJXVNOJCEZCWJV-UHFFFAOYSA-N

Gene Information

human ... TAC1(6863)

Amino Acid Sequence

Ac-Arg-Phe-Phe-Sar-Leu-Met[O]2-NH2

Biochem/physiol Actions

Selective NK-1 receptor agonist.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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New selective agonists for neurokinin receptors: pharmacological tools for receptor characterization.
D Regoli et al.
Trends in pharmacological sciences, 9(8), 290-295 (1988-08-01)
M J Heath et al.
The Journal of physiology, 486 ( Pt 1), 139-148 (1995-07-01)
1. The floor plate is a ventral mid-line structure that plays a pivotal role in the organization of the developing vertebrate central nervous system. Previous studies have demonstrated that the floor plate may provide signals that induce neuronal differentiation and
B J Canning et al.
The Journal of physiology, 480 ( Pt 3), 613-625 (1994-11-01)
1. We recently described a capsaicin-sensitive vagal pathway mediating non-adrenergic, non-cholinergic (NANC) relaxations of an isolated, innervated rostral guinea-pig tracheal preparation. These afferent fibres are carried by the superior laryngeal nerves and relaxations elicited by their activation are insensitive to

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