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P9393

Sigma-Aldrich

Phorbol 12-acetate

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About This Item

Empirical Formula (Hill Notation):
C22H30O7
CAS Number:
70470-59-6
Molecular Weight:
406.47
MDL number:
MFCD00056372
UNSPSC Code:
12352200
PubChem Substance ID:
24899033

storage temp.

−20°C

SMILES string

[H][C@@]12C=C(CO)C[C@]3(O)C(=O)C(C)=C[C@@]3([H])[C@@]1(O)[C@H](C)[C@@H](OC(C)=O)[C@]4(O)[C@H]2C4(C)C

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
064H0590
045H0099
094H0028

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Karl J Hale et al.
Organic letters, 5(4), 499-502 (2003-02-14)
[structure: see text] The synthesis of two truncated bryostatin analogues 2 and 3 is described. High-field NMR measurements on the C-ring analogue 3 in C(2)H(3)CN containing 25% (2)H(2)O have shown that it binds to the CRD2 of human PKC-alpha at
M Ransjö et al.
Calcified tissue international, 49(4), 284-287 (1991-10-01)
Calcitonin (CT) is a well-known inhibitor of osteoclastic bone resorption both in vivo and in vitro. The effect is mediated by activation of adenylate cyclase and subsequent increased levels of cyclic AMP (cAMP). We report here that CT-induced (30 nmol/liter)
S Kleis-San Francisco et al.
Gamete research, 21(3), 323-334 (1988-11-01)
In ovarian follicles of Rana pipiens, frog pituitary homogenates (FPH) elevate intrafollicular progesterone levels which in turn is thought to induce meiotic resumption in the prophase I arrested oocytes. Calcium plays a role in FPH and steroid-provoked responses in the
Chang Xie et al.
American journal of physiology. Cell physiology, 297(5), C1236-C1248 (2009-08-14)
Kv4.3, with its complex open- and closed-state inactivation (CSI) characteristics, is a primary contributor to early cardiac repolarization. The two alternatively spliced forms, Kv4.3-short (Kv4.3-S) and Kv4.3-long (Kv4.3-L), differ by the presence of a 19-amino acid insert downstream from the
J L Tilly et al.
Biology of reproduction, 39(1), 1-8 (1988-08-01)
A series of studies was conducted to evaluate the effects of phorbol esters and a diacylglycerol analog on basal and hormone-stimulated steroidogenesis in granulosa cells from the largest preovulatory follicle of the domestic hen. Agents that previously have been shown
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