P8782
cis-2,3-Piperidinedicarboxylic acid
solid, ≥97% (NMR)
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About This Item
Empirical Formula (Hill Notation):
C7H11NO4
CAS Number:
Molecular Weight:
173.17
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
assay
≥97% (NMR)
form
solid
color
white
solubility
H2O: ≥15 mg/mL
SMILES string
OC(=O)[C@@H]1CCCN[C@@H]1C(O)=O
Gene Information
human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRINA(2907)
Biochem/physiol Actions
NMDA receptor agonist at the glutamate recognition site.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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M Neal et al.
Investigative ophthalmology & visual science, 39(5), 850-853 (1998-04-16)
To investigate the cellular origin of nitric oxide released from the rabbit retina in response to physiological stimulation with light. The release of nitric oxide from the retina was measured in rabbits anesthetized with urethane. An eye-cup was prepared and
T Priestley et al.
Molecular pharmacology, 46(6), 1191-1196 (1994-12-01)
The N-methyl-D-aspartate (NMDA) receptor is unique among the ligand-gated ion channels, in that the gating process requires the binding of two independent coagonists, glutamate and glycine. Receptor binding experiments have suggested that the coagonist recognition sites interact with one another
Shinji Ueno et al.
Vision research, 46(5), 658-664 (2005-07-26)
The purpose of this study was to determine the contribution of different types of retinal neurons to the d-wave of the primate electroretinogram using pharmacological agents. NMDA + TTX was used to suppress inner retinal activity, and APB and PDA
Yiu-Fai Ng et al.
Documenta ophthalmologica. Advances in ophthalmology, 116(3), 165-176 (2007-08-28)
Multifocal electroretinograms (mfERG) from isoflurane anesthetized pigs were recorded and sequential application of TTX, NMDA, APB and PDA were used to identify contributions to the mfERG from inner retinal neurons, ON-pathway, OFF-pathway and photoreceptors. The cellular origins of the first-order
Nalini V Rangaswamy et al.
Investigative ophthalmology & visual science, 48(10), 4818-4828 (2007-09-28)
To determine flash and background colors that best isolate the photopic negative response (PhNR) and maximize its amplitude in the primate ERG. Photopic full-field flash ERGs were recorded from anesthetized macaque monkeys before and after pharmacologic blockade of Na(+)-dependent spiking
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