P8782
cis-2,3-Piperidinedicarboxylic acid
solid, ≥97% (NMR)
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About This Item
Empirical Formula (Hill Notation):
C7H11NO4
CAS Number:
Molecular Weight:
173.17
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
assay
≥97% (NMR)
form
solid
color
white
solubility
H2O: ≥15 mg/mL
SMILES string
OC(=O)[C@@H]1CCCN[C@@H]1C(O)=O
Gene Information
human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRINA(2907)
Biochem/physiol Actions
NMDA receptor agonist at the glutamate recognition site.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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T Priestley et al.
Molecular pharmacology, 46(6), 1191-1196 (1994-12-01)
The N-methyl-D-aspartate (NMDA) receptor is unique among the ligand-gated ion channels, in that the gating process requires the binding of two independent coagonists, glutamate and glycine. Receptor binding experiments have suggested that the coagonist recognition sites interact with one another
M Neal et al.
Investigative ophthalmology & visual science, 39(5), 850-853 (1998-04-16)
To investigate the cellular origin of nitric oxide released from the rabbit retina in response to physiological stimulation with light. The release of nitric oxide from the retina was measured in rabbits anesthetized with urethane. An eye-cup was prepared and
Gen Miura et al.
Experimental eye research, 89(1), 49-62 (2009-03-03)
This study investigated contributions from the retinal On and Off pathways, and the spiking and nonspiking activity of neurons in those pathways to the pattern ERG of the mouse. Light-adapted pattern and ganzfeld ERGs were recorded from anesthetized C57BL/6 mice
Haohua Qian et al.
Experimental eye research, 91(6), 811-817 (2010-10-27)
Harmonic analysis was used to characterize the rabbit flicker ERG elicited by sinusoidally modulated full-field stimuli under light-adapted conditions. The frequency-response function for fundamental amplitude, derived from Fourier analysis of the ERG waveforms, exhibited two limbs, with an amplitude minimum
D P Crewther et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 12(2), 193-208 (1996-01-01)
The interaction between drugs which affect ON and OFF responses to light and ocular growth was investigated in 154 eyes of newly-hatched chicks raised with normal vision or monocular occlusion with regular intravitreal injections of APB (2-amino-4 phosphonobutyric acid) or
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