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Key Documents

P7380

Sigma-Aldrich

Purpurogallin

Sigma Grade

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About This Item

Empirical Formula (Hill Notation):
C11H8O5
CAS Number:
Molecular Weight:
220.18
EC Number:
MDL number:
UNSPSC Code:
12171500

grade

Sigma Grade

mp

275 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

OC1=CC=Cc2cc(O)c(O)c(O)c2C1=O

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Application

Calibration standard for peroxidase assays using pyrogallol as substrate.

Biochem/physiol Actions

Polyphenol antibiotic originally isolated from Quercus nutgall that has antioxidant activity. Competitive inhibitor of epidermal growth factor receptor protein tyrosine kinase activity; inhibitor of xanthine oxidase.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mairtin O'Coinceanainn et al.
Journal of inorganic biochemistry, 96(4), 463-468 (2003-09-19)
Polyphenols are antioxidants, which are known to influence bioavailability of metals in the body. The theaflavins of black tea are important members of this family, which have been sparsely investigated. The complexation of aluminium with purpurogallin (2,3,4,6-tetrahydroxy-5H-benzocyclohepten-5-one) has been investigated
O Nozaki et al.
Journal of bioluminescence and chemiluminescence, 10(3), 151-156 (1995-05-01)
The effects of various boronate compounds, 4-biphenylboronic acid, 4-bromobenzene-boronic acid, trans-4-(3-propionic acid)phenylboronic acid and 4-iodophenylboronic acid, on the horseradish peroxidase (HRP) catalysed chemiluminescent oxidation of pyrogallol and purpurogallin by peroxide were investigated. trans-4-(3-Propionic acid)phenylboronic acid produced a 13.7-fold enhancement in
Akram Jamshidzadeh et al.
Journal of applied toxicology : JAT, 27(4), 322-326 (2007-02-01)
Chloroquine is a synthetic quinoline being used as an antimalaria and antirheumatoid agent. Several cases of hepatotoxicity have been reported with the use of chloroquine. However, the mechanism(s) of its hepatotoxic effect is unknown. The purpose of this study was
L H Zeng et al.
Cornea, 14(5), 509-514 (1995-09-01)
We reported previously that purpurogallin (PPG) markedly protects the cultured rabbit corneal endothelial cells (RCEC) against oxyradical damage generated with hypoxanthine (HX) and xanthine oxidase (XO)(1). In this study, we further compared the cytoprotective activities of PPG versus Trolox (TX
Shinichi Kitada et al.
Journal of medicinal chemistry, 46(20), 4259-4264 (2003-09-19)
Among the most promising chemopreventive agents, certain natural polyphenols have recently received a great deal of attention because of their demonstrated inhibitory activity against tumorigenesis. In view of their anticancer properties, these compounds also hold great promise as potential chemotherapeutic

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