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About This Item
Empirical Formula (Hill Notation):
C16H23N3O4
CAS Number:
Molecular Weight:
321.37
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
storage temp.
−20°C
SMILES string
NCCCCC(NC(=O)CNC(=O)Cc1ccccc1)C(O)=O
InChI
1S/C16H23N3O4/c17-9-5-4-8-13(16(22)23)19-15(21)11-18-14(20)10-12-6-2-1-3-7-12/h1-3,6-7,13H,4-5,8-11,17H2,(H,18,20)(H,19,21)(H,22,23)
InChI key
VPCYMTNCRVUYFU-UHFFFAOYSA-N
Other Notes
Peptide that is 50 times sweeter than sucrose
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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J A Aquilina et al.
Biochemistry, 38(35), 11455-11464 (1999-09-02)
3-Hydroxykynurenine, a metabolite of tryptophan, is a powerful antioxidant and neurotoxin. The neurotoxicity results from the oxidation of 3-hydroxykynurenine, and hydroxyl radicals, formed via H(2)O(2), may also be implicated [Okuda, S., Nishiyama, N., Saito, H. , and Katsuki, H. (1996)
J A Aquilina et al.
Biochemistry, 39(51), 16176-16184 (2000-12-22)
3-Hydroxykynurenine (3OHKyn) is present in the mammalian lens as a UV filter and is formed from kynurenine in the tryptophan metabolic pathway. 3OHKyn is a readily autoxidized o-aminophenol which binds to proteins in vitro. The lens, particularly its central region
Nosho, Y. and Ohfuji, T.
Chemical and Engineering News, 68(2), 25-25 (1990)
Magdalena M Staniszewska et al.
The Journal of biological chemistry, 280(23), 22154-22164 (2005-04-09)
Tryptophan can be oxidized in the eye lens by both enzymatic and non-enzymatic mechanisms. Oxidation products, such as kynurenines, react with proteins to form yellow-brown pigments and cause covalent cross-linking. We generated a monoclonal antibody against 3-hydroxykynurenine (3OHKYN)-modified keyhole limpet
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