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P2375

Sigma-Aldrich

D-Panthenol

≥98% (perchloric acid titration), ≥98% (TLC)

Synonym(s):

(R)-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, (R)-2,4-Dihydroxy-3,3-dimethylbutyric 3-hydroxypropylamide, D-Pantothenyl alcohol, Dexpanthenol, Provitamin B

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About This Item

Empirical Formula (Hill Notation):
C9H19NO4
CAS Number:
81-13-0
Molecular Weight:
205.25
Beilstein/REAXYS Number:
1724947
EC Number:
201-327-3
MDL number:
MFCD00065006
UNSPSC Code:
12352200
PubChem Substance ID:
329820134

biological source

synthetic (organic)

assay

≥98% (TLC)
≥98% (perchloric acid titration)

form

liquid
semisolid

color

colorless to white

density

1.20 g/mL at 20 °C (lit.)

storage temp.

−20°C

SMILES string

CC(C)(CO)[C@@H](O)C(=O)NCCCO

InChI

1S/C9H19NO4/c1-9(2,6-12)7(13)8(14)10-4-3-5-11/h7,11-13H,3-6H2,1-2H3,(H,10,14)/t7-/m0/s1

InChI key

SNPLKNRPJHDVJA-ZETCQYMHSA-N

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replaced by

Product No.
Description
Pricing

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
120K2602
101K2500
085F06171
084K2515
075K2517

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M Göbbels et al.
Klinische Monatsblatter fur Augenheilkunde, 209(2-3), 84-88 (1996-08-01)
In this controlled, randomized, double-masked study the effect of dexpanthenol-containing artificial tears (Siccaprotect) on patients with dry eyes was examined. 50 patients applied either dexpanthenol-containing artificial tears (Siccaprotect) or the identical, but free of dexpanthenol, eye drops five times daily
M Sachs et al.
Zeitschrift fur Ernahrungswissenschaft, 29(4), 270-283 (1990-12-01)
The aim of this study was the examination of the metabolism and mechanism of action of D-pantothenyl alcohol in patients with postoperative intestinal atony. Seven metabolically healthy patients were examined on the 4th day following colorectal surgery, before bowel activity
Fritz Ebner et al.
American journal of clinical dermatology, 3(6), 427-433 (2002-07-13)
Pantothenic acid is essential to normal epithelial function. It is a component of coenzyme A, which serves as a cofactor for a variety of enzyme-catalyzed reactions that are important in the metabolism of carbohydrates, fatty acids, proteins, gluconeogenesis, sterols, steroid
W Gehring et al.
Arzneimittel-Forschung, 50(7), 659-663 (2000-08-31)
In a randomized, double-blind, placebo-controlled study the effect of topical dexpanthenol (CAS 81-13-0) formulated in two different lipophilic vehicles on epidermal barrier function in vivo was carried out. Seven days' treatment with dexpanthenol improved stratum corneum hydration and reduced transepidermal

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