N6136

Nickel(II) chloride hexahydrate

BioReagent, suitable for cell culture

• Synonym(s): NiCl₂.6H₂O, Nickel chloride hexahydrate, Nickel dichloride hexahydrate
• Linear Formula: NiCl₂ · 6H₂O
• CAS Number: 7791-20-0
• Molecular Weight: 237.69
• MDL number: MFCD00149809
• UNSPSC Code: 12352207
• PubChem Substance ID: 24897771
• NACRES: NA.71
• form: powder

Properties

• product line: BioReagent
• Quality Level: 200
• form: powder
• technique(s): cell culture | mammalian: suitable
• SMILES string: [H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].Cl[Ni]Cl
• InChI: 1S/2ClH.Ni.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2
• InChI key: LAIZPRYFQUWUBN-UHFFFAOYSA-L

Description

Application

Nickel(II) chloride hexahydrate has been used:

• in the preparation of nickel platting solution for galvanostatically coating nickel inside the reduced carbon layer during the synthesis of multiwall carbon nanotube micromotors[1]
• in screening of metals for inflammatory effect on vascular endothelial cells[2]
• as an additive in artificial cerebrospinal fluid (ACSF) to analyse excitatory post synaptic currents (EPSPs) in the hippocampus slices[3]

Biochem/physiol Actions

Nickel (Ni) is an essential trace element that plays an important role in the structure and function of DNA, RNA and protein. It has toxic effects on renal, pulmonary and cardiovascular system at higher concentrations.[4] Nickel is implicated in carcinogenesis.[5] Ni²⁺ ions is a clastogenic agent.[6] Nickel ions (Ni²⁺) is a non-specific voltage-gated calcium channel blocker.[7]

Safety Information

• pictograms: GHS06,GHS08,GHS09
• signalword: Danger
• hcodes: H301 + H331,H315,H317,H334,H341,H350i,H360D,H372,H410
• pcodes: P202 - P273 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A Inhalation - Muta. 2 - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Inhalation
• target_organs: Lungs
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges