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M6514

Sigma-Aldrich

3-(Trimethoxysilyl)propyl methacrylate

≥97%

Synonym(s):

Silane A174, [3-(Methacryloyloxy)propyl]trimethoxysilane

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50 ML
$103.00

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25 ML
$68.20
50 ML
$103.00

About This Item

Linear Formula:
H2C=C(CH3)CO2(CH2)3Si(OCH3)3
CAS Number:
2530-85-0
Molecular Weight:
248.35
Beilstein/REAXYS Number:
1952435
EC Number:
219-785-8
MDL number:
MFCD00008593
UNSPSC Code:
47101511
PubChem Substance ID:
24897091
NACRES:
NA.56

$68.20

In StockDetails

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Quality Level

100

assay

≥97%

form

liquid

refractive index

n20/D 1.431 (lit.)

bp

190 °C (lit.)

density

1.045 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CO[Si](CCCOC(=O)C(C)=C)(OC)OC

InChI

1S/C10H20O5Si/c1-9(2)10(11)15-7-6-8-16(12-3,13-4)14-5/h1,6-8H2,2-5H3

InChI key

XDLMVUHYZWKMMD-UHFFFAOYSA-N

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General description

3-(Trimethoxysilyl)propyl methacrylate (TMSPMA) is a hydrophobic monomer.[1] The presence of an additional functional group of acrylate facilitates TMSPMA for grafting polymerization on plastic surfaces.[2] 3-(Trimethoxysilyl)propyl methacrylate undergoes first-order kinetic polymerization to form polyTMSPMA, which is a moisture stable polymer.[3]

Application

3-(Trimethoxysilyl)propyl methacrylate has been used in the following applications:
  • Isoelectric focusing can lead to pH gradient formation resulting in the swelling or shrinking of gel casts. This can be prevented by using 3-(Trimethoxysilyl)propyl methacrylate to link polyacrylamide gels to glass plates covalently.[4]
  • In situ hybridization using 3-(Trimethoxysilyl)propyl methacrylate along with poly-L-lysine is a faster and durable method to attach cells, microscopic sections, and total organs to slides/other glass surfaces.[5]
  • 3-(Trimethoxysilyl)propyl methacrylate is also used in the preparation of organic/inorganic hybrid nanomaterials.[6]

Packaging

A product Information sheet is supplied which describes procedures for using this product.

Related product

Product No.
Description
Pricing

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

197.6 °F - closed cup

flash_point_c

92 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT4433
MKCR5502
MKCK3155
MKCG8995
MKBX0874V

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Preparation of organic/inorganic hybrid nanomaterials using aggregates of poly (stearyl methacrylate)-b-poly (3-(trimethoxysilyl) propyl methacrylate) as precursor.
Junfeng Zhou.
Eur. Polymer J., 5, 1736-1743 (2007)
Improvements of DNA sequencing gels.
H Garoff et al.
Analytical biochemistry, 115(2), 450-457 (1981-08-01)
Saisneha Koppaka et al.
Micromachines, 12(9) (2021-09-29)
Micro-blade design is an important factor in the cutting of single cells and other biological structures. This paper describes the fabrication process of three-dimensional (3D) micro-blades for the cutting of single cells in a microfluidic "guillotine" intended for fundamental wound
Bozhen Zhang et al.
Journal of materials chemistry. B, 9(35), 7196-7204 (2021-07-23)
Label-free cell sorting devices are of great significance for biomedical research and clinical therapeutics. However, current platforms for label-free cell sorting cannot achieve continuity and selectivity simultaneously, resulting in complex steps and limited reliability. Here, an immunoaffinity-based cell catch-transport-release thermo-chemo-mechanical
Method for attachment of microscopic preparations on glass for in situ hybridization, PRINS and in situ PCR studies.
H M Dyanov et al.
BioTechniques, 18(5), 822-824 (1995-05-01)
View All Related Papers

Questions

  1. How stable is this product? How many years will it be good if kept at 2 degrees C?

    1 answer

    1. The product remains active for at least 2 years. This product will react with water since alkylsilanes react with hydroxyl groups. An ethanol solution remains active for one day. For more information please see this data sheet: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/139/774/m6514pis.pdf.

      The product specification sheet for this product contains a recommended retest date period of two years after the quality release date. A recommended retest date is the period of time during which the product is expected to remain within established stability specifications, provided that it has been stored under defined conditions. After the Retest Date, product samples should be examined to ensure that the product is still in compliance with the established specifications. For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services.

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