M3191
Myoseverin
≥97% (HPLC), solid
Synonym(s):
9-Isoproyl-N2,N6-bis-(4-methoxybenxyl)-9H-purine-2,6-diamine
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About This Item
Empirical Formula (Hill Notation):
C24H28N6O2
CAS Number:
Molecular Weight:
432.52
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
assay
≥97% (HPLC)
form
solid
color
off-white
solubility
chloroform: soluble 50 mg/mL
shipped in
dry ice
storage temp.
−20°C
SMILES string
COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C(C)C)c4n2)cc1
Biochem/physiol Actions
Myoseverin, a 2,6,9 trisubstituted purine, is a microtuble-binding molecule and reversible inhibitor of tubulin polymerization. It arrests cell cycle in the G2/M phase and causes mature, terminally differentiated mouse myotubes to disassemble into mononucleated fragments capable of responding to growth and differentiation conditions.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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