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Key Documents

M1818

Sigma-Aldrich

Molindone hydrochloride

≥98% (HPLC), solid

Synonym(s):

3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H24N2O2 · HCl
CAS Number:
Molecular Weight:
312.83
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

Quality Level

assay

≥98% (HPLC)

form

solid

color

off-white

solubility

H2O: 19 mg/mL

originator

Endo

SMILES string

CCC1=C(C)NC2=C1C(C(CN3CCOCC3)CC2)=O.Cl

InChI

1S/C16H24N2O2.ClH/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18;/h12,17H,3-10H2,1-2H3;1H

InChI key

GQWNECFJGBQMBO-UHFFFAOYSA-N

Gene Information

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Biochem/physiol Actions

D2 dopamine receptor antagonist; MAO inhibitor.

Features and Benefits

This compound was developed by Endo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Aripiprazole-induced agitation after clozapine discontinuation: a case report.
Dara Y Cho et al.
The Journal of clinical psychiatry, 70(1), 141-143 (2009-02-19)
H B Pinkofsky
Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 9(3), 175-179 (1997-10-27)
The onset of psychosis during pregnancy presents several difficult management decisions and a careful risk-benefit analysis is required. Withholding antipsychotic treatment may produce more risks than benefits. Studies on neuroleptic teratogenicity are contradictory. Most of the commonly used neuroleptics exhibit
Treatment of morbidly obese psychotic patients with molindone: three case reports.
Robert E McCue et al.
The Journal of clinical psychiatry, 70(11), 1606-1607 (2009-12-25)
Jon McClellan et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 46(8), 969-978 (2007-08-02)
The Treatment of Early Onset Schizophrenia Spectrum Disorders Study is a publicly funded clinical trial designed to compare the therapeutic benefits, safety, and tolerability of risperidone, olanzapine, and molindone in youths with early-onset schizophrenia spectrum disorders. The rationale, design, and
R B Rosse et al.
Clinical neuropharmacology, 19(5), 444-450 (1996-10-01)
This preliminary investigation examined the therapeutic efficacy of two doses of oral D-cycloserine (5 and 15 mg p.o. b.i.d.) administered as an adjuvant to molindone (150 mg p.o. q.d.) in the treatment of schizophrenia. D-Cycloserine is an agonist at the

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