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Key Documents

L4131

Sigma-Aldrich

Lanthanum(III) chloride heptahydrate

≥99.9%

Synonym(s):

Lanthanum trichloride heptahydrate

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About This Item

Linear Formula:
LaCl3 · 7H2O
CAS Number:
Molecular Weight:
371.37
MDL number:
UNSPSC Code:
12352302

assay

≥99.9%

mp

91 °C (dec.) (lit.)

SMILES string

O.O.O.O.O.O.O.Cl[La](Cl)Cl

InChI

1S/3ClH.La.7H2O/h3*1H;;7*1H2/q;;;+3;;;;;;;/p-3

InChI key

FDFPDGIMPRFRJP-UHFFFAOYSA-K

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Biochem/physiol Actions

Calcium channel blocker

signalword

Danger

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Sens. 1

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk_germany

WGK 2

flash_point_f

does not flash

flash_point_c

does not flash

ppe

dust mask type N95 (US), Eyeshields, Gloves


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J E Huettner et al.
Neuropharmacology, 37(10-11), 1239-1247 (1998-12-16)
The effects of lanthanum and gadolinium on currents evoked by excitatory amino acids were studied in cultured rat hippocampal and cortical neurons, in freshly dissociated dorsal root ganglion neurons, and in human embryonic kidney 293 cells expressing the GluR6 kainate
Anna Citta et al.
Journal of inorganic biochemistry, 117, 18-24 (2012-10-20)
Lanthanum chloride (LaCl(3)) is a good inhibitor of both the cytosolic and mitochondrial thioredoxin reductase with IC(50) values of 1.75 and 7.46 μM, respectively. On the contrary, the related enzyme glutathione reductase is not inhibited by lanthanum ions even at
Jinghua Yang et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 26(1), 43-59 (2012-10-26)
Lanthanum chloride (LaCl(3)) can affect neurobehavioral development and impair cognitive abilities. The mechanism underlying LaCl(3)-induced neurotoxic effects is still unknown. The purpose of this research was to investigate the neuronal impairment induced by LaCl(3) and discuss the possible mechanism from
Mario Pink et al.
Electrophoresis, 34(4), 501-504 (2012-11-30)
The recent introduction of the La(3+) precipitation method for the enrichment of phosphoproteins allows a gel-based analysis of these posttranslationally modified proteins. However, if this method is applied to cell lysates stored in urea-containing lysis buffer for an extended period
Yasuhiko Suzuki et al.
Biochemical and biophysical research communications, 410(2), 317-321 (2011-06-15)
Bradykinin (BK), a mediator of pain and inflammation, is involved in bone metabolism. We have previously reported that BK increased the synthesis of interleukin-6 and prostaglandin E(2) via phosphorylation of ERK1/2 in human osteoblasts, SaM-1. In the present study, we

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