Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

L3398

Sigma-Aldrich

Luteinizing hormone releasing hormone Fragment 7-10 dihydrochloride

≥97% (HPLC)

Synonym(s):

LH-RH Fragment 7-10 dihydrochloride, Leu-Arg-Pro-Gly-NH2

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C19H36N8O4 · 2HCl
CAS Number:
75690-75-4
Molecular Weight:
513.46
MDL number:
MFCD00133509
UNSPSC Code:
12352200
PubChem Substance ID:
24896340
assay:
≥97% (HPLC)

assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

Cl.CC(C)CC(N)C(=O)NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)NCC(N)=O

InChI

1S/C19H36N8O4.ClH/c1-11(2)9-12(20)16(29)26-13(5-3-7-24-19(22)23)18(31)27-8-4-6-14(27)17(30)25-10-15(21)28;/h11-14H,3-10,20H2,1-2H3,(H2,21,28)(H,25,30)(H,26,29)(H4,22,23,24);1H

InChI key

JKIOGUIXJNHXTH-UHFFFAOYSA-N

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360

Hazard Classifications

Repr. 1B

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
070H0225
070H02251
070H02253
070H02252

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Sudhir N Umathe et al.
Behavioural pharmacology, 19(4), 308-316 (2008-07-16)
The correlation between neuronal mechanism of anxiety and neuroanatomic expression/neuromodulatory role of gonadotropin-releasing hormone (GnRH), points to a role of GnRH in the modulation of anxiety. Therefore, we investigated the influence of GnRH agonists and antagonist on the anxiety-like behavior
Non-peptidic GnRH receptor antagonists.
Armer RE, Smelt KH.
Current Medicinal Chemistry, 11, 33017-33028 (2004)
R P Millar et al.
British medical bulletin, 56(3), 761-772 (2001-03-20)
Gonadotropin-releasing hormone (GnRH) is a decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) which is produced from a precursor polypeptide in hypothalamic neurons and secreted in a pulsatile fashion to stimulate the secretion of LH and FSH via its interaction with a cognate receptor on gonadotropes.
V Singh
Biochemistry and cell biology = Biochimie et biologie cellulaire, 64(12), 1372-1377 (1986-12-01)
Immunochemical studies on monoclonal and conventional anti-LHRH antibodies have been reported. The association constants (Ka) were in the order of 10(9)-10(10) L/mol when calculated from Scatchard and Steward-Petty plots. Heterogeneity indices (a) calculated from Sips plot were nearly 1.0, indicating

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service