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I7006

Sigma-Aldrich

Bis(3-aminopropyl)amine

Synonym(s):

3,3′-Diaminodipropylamine, 3,3′-Iminodipropylamine, N-(3-Aminopropyl)-1,3-propanediamine, Dipropylenetriamine, Norspermidine

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About This Item

Linear Formula:
(NH2CH2CH2CH2)2NH
CAS Number:
56-18-8
Molecular Weight:
131.22
Beilstein/REAXYS Number:
1071254
EC Number:
200-261-2
MDL number:
MFCD00008214
UNSPSC Code:
12352100
PubChem Substance ID:
24896102

refractive index

n20/D 1.481 (lit.)

bp

151 °C/50 mmHg (lit.)

mp

−14 °C (lit.)

density

0.938 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

NCCCNCCCN

InChI

1S/C6H17N3/c7-3-1-5-9-6-2-4-8/h9H,1-8H2

InChI key

OTBHHUPVCYLGQO-UHFFFAOYSA-N

Gene Information

mouse ... Odc1(18263)

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signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Muta. 2 - Skin Corr. 1A - Skin Sens. 1A - STOT RE 2

target_organs

thymus

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 2

flash_point_f

242.6 °F - closed cup

flash_point_c

117 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Johannes Ghatnekar et al.
Bioorganic & medicinal chemistry, 15(23), 7426-7433 (2007-09-18)
We here report the synthesis of the two polyamine-based nucleoside derivatives 5-{[bis-(3-aminopropyl)amino]acetamido-1-propynyl}uridine and 2-{[bis-(3-aminopropyl)amino]-acetamido-1-propynyl}adenosine. The various polyamine derivatives have been used in thermal melting analysis using DNA from herring testes, and in cellular studies using four different cell lines. The
T Yorifuji et al.
Journal of biochemistry, 122(3), 537-543 (1997-11-05)
Polyamine aminotransferase of Arthrobacter sp. TMP-1 was induced by 1,3-diaminopropane (DAP), N-3-aminopropyl-1,3-diaminopropane (norspermidine), spermidine, and spermine, but not by putrescine. The enzyme was purified to homogeneity. Its molecular weight and subunit size were 129,000 and 64,000, respectively. Its absorption spectrum
T Shinki et al.
European journal of biochemistry, 183(2), 285-290 (1989-08-01)
We have reported that spermidine N1-acetyltransferase has a larger role than ornithine decarboxylase in putrescine synthesis in chick duodenum induced by 1 alpha,25-dihydroxycholecalciferol (calcitriol) [Shinki, T., Kadofuku, T., Sato, T. and Suda, T. (1986) J. Biol. Chem. 261, 11712-11716]. In
Ece Karatan et al.
Journal of bacteriology, 187(21), 7434-7443 (2005-10-21)
Vibrio cholerae is both an environmental bacterium and a human intestinal pathogen. The attachment of bacteria to surfaces in biofilms is thought to be an important feature of the survival of this bacterium both in the environment and within the
N J Prakash et al.
Anticancer research, 8(4), 563-568 (1988-07-01)
The structural specificities of the natural polyamines putrescine (Put), spermidine (Spd) and spermine (Spm) for cell growth are rather stringent, suggesting that appropriate structural analogues of these polycations could serve as potential antineoplastic agents via polyamine antagonism. Norspermidine (Nspd), a
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