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I2656

Sigma-Aldrich

Insulin-like Growth Factor-I (E3R) human

>95% (HPLC), recombinant, expressed in E. coli, lyophilized powder

Synonym(s):

IGF-I (E3R)

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About This Item

MDL number:
UNSPSC Code:
12352204
NACRES:
NA.83

biological source

human

recombinant

expressed in E. coli

assay

>95% (HPLC)

form

lyophilized powder

mol wt

7.6 kDa

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... IGF1(3479)

Biochem/physiol Actions

IGF1(3R) contains the amino acid substitution E3R, which decreases binding to IGF-binding proteins. IGF1(3R) therefore is much more potent than the native IFG1.

Physical form

Lyophilzed from a solution in 0.1 M acetic acid.

Analysis Note

The biological activity is assayed using L6 myoblasts.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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D LeRoith et al.
Annals of the New York Academy of Sciences, 692, 1-9 (1993-08-27)
The purpose of this review has been to emphasize, in general terms, the major aspects of the structure, expression, and regulation of the IGF-I and IGF-II genes. The complex organization of these genes provides ample opportunities for control of gene

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