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Key Documents

I2250

Sigma-Aldrich

Indole-5-carboxylic acid

~95% (TLC)

Synonym(s):

5-Carboxyindole

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About This Item

Empirical Formula (Hill Notation):
C9H7NO2
CAS Number:
Molecular Weight:
161.16
Beilstein/REAXYS Number:
124391
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

assay

~95% (TLC)

mp

211-213 °C (lit.)

storage temp.

−20°C

SMILES string

OC(=O)c1ccc2[nH]ccc2c1

InChI

1S/C9H7NO2/c11-9(12)7-1-2-8-6(5-7)3-4-10-8/h1-5,10H,(H,11,12)

InChI key

IENZCGNHSIMFJE-UHFFFAOYSA-N

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Application

  • Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators
  • Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction
  • Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst
  • Reactant for synthesis of indirubin derivatives
  • Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway
  • Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity

replaced by

Product No.
Description
Pricing

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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