Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

H9267

Sigma-Aldrich

Heparin disaccharide I-S sodium salt

sulfated heparin fragment

Synonym(s):

α-ΔUA-2S-[1→4]-GlcNS-6S

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C12H15NO19S3Na4
CAS Number:
136098-10-7
Molecular Weight:
665.40
MDL number:
MFCD00466927
UNSPSC Code:
12352201
PubChem Substance ID:
24895847
NACRES:
NA.25

Quality Level

200

assay

≥98%

form

powder

technique(s)

HPLC: suitable

storage temp.

−20°C

SMILES string

[Na].OC(COS(O)(=O)=O)C(OC1OC(=CC(O)C1OS(O)(=O)=O)C(O)=O)C(O)C(NS(O)(=O)=O)C=O

InChI

1S/C12H19NO19S3.Na.H/c14-2-4(13-33(20,21)22)8(17)9(6(16)3-29-34(23,24)25)31-12-10(32-35(26,27)28)5(15)1-7(30-12)11(18)19;;/h1-2,4-6,8-10,12-13,15-17H,3H2,(H,18,19)(H,20,21,22)(H,23,24,25)(H,26,27,28);;

InChI key

QNESCZPGLNWDJH-UHFFFAOYSA-N

Biochem/physiol Actions

Products of the digestion of heparin and heparan sulfate by various heparinases

Other Notes

In the following listings, ΔUA = 4-deoxy-L-threo-hex-4-enopyranosyluronic acid; GlcN = D-glucosamine; Ac = Acetyl; NS, 2S, 6S, = N-sulfo, 2-sulfate and 6-sulfate respectively.
To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Preparation Note

Produced by the action of heparinase I and II

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Yi Xue et al.
The Journal of biological chemistry, 286(34), 29748-29757 (2011-07-01)
Missense mutations in the amyloid precursor protein (APP) gene can cause familial Alzheimer disease. It is thought that APP and APP-like proteins (APLPs) may play a role in adhesion and signal transduction because their ectodomains interact with components of the
Julia P Steringer et al.
eLife, 6 (2017-07-20)
FGF2 is secreted from cells by an unconventional secretory pathway. This process is mediated by direct translocation across the plasma membrane. Here, we define the minimal molecular machinery required for FGF2 membrane translocation in a fully reconstituted inside-out vesicle system.
Hector Moreno et al.
PLoS neglected tropical diseases, 14(12), e0009004-e0009004 (2020-12-29)
A detailed understanding of the mechanisms underlying the capacity of a virus to break the species barrier is crucial for pathogen surveillance and control. New World (NW) mammarenaviruses constitute a diverse group of rodent-borne pathogens that includes several causative agents

Articles

Glycosaminoglycan Sulfation and Signaling

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service