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Key Documents

H6769

Sigma-Aldrich

Hirudin Fragment 54-65 non-sulfated

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C66H93N13O25
CAS Number:
Molecular Weight:
1468.52
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CCC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(O)=O)NC(=O)CN)C(=O)N2CCCC2C(=O)NC(CCC(O)=O)C(=O)NC(CCC(O)=O)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(O)=O

Amino Acid Sequence

Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln

Biochem/physiol Actions

Hirudin fragment that binds to the regulatory exosite I (proexosite I) on prothrombin with lower affinity than the sulfated peptide. It inhibits the activation of prothrombin by factor Xa in the presence of factor Va.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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