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H177

Sigma-Aldrich

2-Hydroxytetradecanoic acid

powder

Synonym(s):

2-Hydroxymyristic acid, DL-α-Hydroxymyristic acid

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About This Item

Empirical Formula (Hill Notation):
C14H28O3
CAS Number:
2507-55-3
Molecular Weight:
244.37
Beilstein/REAXYS Number:
1725369
EC Number:
219-714-0
MDL number:
MFCD00014342
UNSPSC Code:
12352200

form

powder

color

white

solubility

DMSO: 4 mg/mL (with heating in a 70°C water bath)
H2O: 5 mg/mL

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCC(O)C(O)=O

InChI

1S/C14H28O3/c1-2-3-4-5-6-7-8-9-10-11-12-13(15)14(16)17/h13,15H,2-12H2,1H3,(H,16,17)

InChI key

JYZJYKOZGGEXSX-UHFFFAOYSA-N

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A B Vaandrager et al.
The Journal of biological chemistry, 271(12), 7025-7029 (1996-03-22)
The apical membrane of intestinal epithelial cells harbors a unique isozyme of cGMP-dependent protein kinase (cGK type II) which acts as a key regulator of ion transport systems, including the cystic fibrosis transmembrane conductance regulator (CFTR)-chloride channel. To explore the
M J Nadler et al.
Biochemistry, 32(35), 9250-9255 (1993-09-07)
N-Myristoylation of p56lck, a member of the Src family of protein-tyrosine kinases, is essential for its proper targeting to the plasma membrane. 2-Hydroxymyristic acid (HMA) is an analog of myristic acid that becomes metabolically activated in cells to form 2-hydroxymyristoyl-CoA
L A Paige et al.
Biochemistry, 29(46), 10566-10573 (1990-11-20)
The importance of myristoylation for the proper biological functioning of many acylated proteins has generated interest in the enzymes of the myristoylation pathway and their interactions with substrates and inhibitors. Previous observations that S-(2-oxopentadecyl)-CoA, a nonhydrolyzable methylene-bridged analogue of myristoyl-CoA

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