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G5630

Sigma-Aldrich

Gly-Gly-Gly-Gly-Gly-Gly

solid

Synonym(s):

Hexaglycine

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About This Item

Empirical Formula (Hill Notation):
C12H20N6O7
CAS Number:
Molecular Weight:
360.32
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.26

product name

Gly-Gly-Gly-Gly-Gly-Gly,

form

solid

color

white

mp

314.5 °C

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(O)=O

InChI

1S/C12H20N6O7/c13-1-7(19)14-2-8(20)15-3-9(21)16-4-10(22)17-5-11(23)18-6-12(24)25/h1-6,13H2,(H,14,19)(H,15,20)(H,16,21)(H,17,22)(H,18,23)(H,24,25)

InChI key

XJFPXLWGZWAWRQ-UHFFFAOYSA-N

Application

Hexaglycine and capped hexaglycine are used in physicochemical studies of peptide structure dynamics. Hexaglycine is used as a model compound in development of peptide quantitation and separation methods.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Analyst, 135(6), 1456-1460 (2010-05-26)
A novel method is presented for the quantitation of peptides based on their methylation by in vacuo chemical reaction with methyl iodide. Samples of two small peptides, hexaglycine and pentaalanine, were labeled with CH(3)I and CD(3)I, representing the "unknown" and
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The journal of physical chemistry. B, 115(6), 1562-1570 (2011-01-26)
We compare the energies and enthalpies of inter-action of three- and seven-stranded capped polyglycine aggregates in both the pleated and rippled antiparallel and parallel β-sheet structures as well as the collagenic (three-strand) or polyglycine II-like (seven-strand) forms using density functional
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Journal of the American Society for Mass Spectrometry, 25(10), 1716-1729 (2014-07-30)
It is shown that y-type ions, after losing C-terminal H2O or NH3, can lose an internal backbone carbonyl (CO) from different peptide positions and yield structurally different product fragment ions upon collision-induced dissociation (CID). Such CO losses from internal peptide

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