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F6932

Sigma-Aldrich

Fucoxanthin

carotenoid antioxidant

Synonym(s):

all-trans-Fucoxanthin

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10 MG
$217.00
50 MG
$860.00

About This Item

Empirical Formula (Hill Notation):
C42H58O6
CAS Number:
Molecular Weight:
658.91
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.25

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Quality Level

assay

≥95% (HPLC)

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

CC(=O)O[C@H]1CC(C)(C)C(=C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(/C)C(=O)C[C@@]23O[C@]2(C)C[C@@H](O)CC3(C)C)[C@](C)(O)C1

InChI

1S/C42H58O6/c1-29(18-14-19-31(3)22-23-37-38(6,7)26-35(47-33(5)43)27-40(37,10)46)16-12-13-17-30(2)20-15-21-32(4)36(45)28-42-39(8,9)24-34(44)25-41(42,11)48-42/h12-22,34-35,44,46H,24-28H2,1-11H3/b13-12+,18-14+,20-15+,29-16+,30-17+,31-19+,32-21+/t23-,34-,35-,40+,41+,42-/m0/s1

InChI key

SJWWTRQNNRNTPU-XJUZQKKNSA-N

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General description

Fucoxanthin is isolated from brown algae. It has anti-angiogenic,[1] hepatoprotective, cardiovascular and cerebrovascular protective properties. Fucoxanthin stimulates G1 cell-cycle arrest and apoptosis in cancer cell lines.[2]

Application

Fucoxanthin has been used to study its neuroprotective effects.[3][4] It has also been used in calibration to identify the most efficient fucoxanthin producing strains of microalgae.[5]

Biochem/physiol Actions

Xanthophyll carotenoid pigment extracted from algae. Exhibits anticancer, antioxidant, anti-obesity and anti-inflammatory properties.

related product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Bingbing Guo et al.
Pharmaceuticals (Basel, Switzerland), 14(10) (2021-10-24)
Non-alcoholic fatty liver disease (NAFLD), characterized by hepatic steatosis, is one of the most common liver diseases worldwide. So far, no definitive medical treatment has been established to treat NAFLD except for lifestyle medication. Nitzschia laevis extract (NLE), a microalgal
Adah Fung et al.
Food chemistry, 136(2), 1055-1062 (2012-11-06)
This study investigated the fucoxanthin content of New Zealand (NZ) Undaria pinnatifida harvested from two locations in the Marlborough Sounds, New Zealand across its growing season. Fucoxanthin content and antioxidant properties of processed New Zealand U. pinnatifida and commercial wakame
Ching-Shu Lai et al.
Journal of agricultural and food chemistry, 60(4), 1094-1101 (2012-01-10)
Xanthigen is a source of punicic acid and fucoxanthin derived from pomegranate seed and brown seaweed, respectively with recognized triacylglycerol-lowering effects in humans, yet the mechanism remains to be fully elucidated. The present study investigated the inhibitory effects of Xanthigen
Lavanya Premvardhan et al.
The journal of physical chemistry. B, 112(37), 11838-11853 (2008-08-30)
Fucoxanthin chlorophyll-a/c 2 protein (FCP), the membrane-intrinsic light harvesting complex from the diatom Cyclotella meneghiniana, is characterized by Stark spectroscopy to obtain a quantitative measure of the excited-state dipolar properties of the constituent pigments. The electro-optical properties of the carotenoid
Soo-Jin Heo et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(9), 3336-3342 (2012-06-28)
In this study, the anti-inflammatory effect of fucoxanthin (FX) derivatives, which was isolated from Sargassum siliquastrum were evaluated by examining their inhibitory effects on pro-inflammatory mediators in lipopolysaccharide (LPS)-stimulated murine macrophage RAW 264.7 cells. The FX derivatives were isolated from

Questions

  1. What is the solubility of this substance?

    1 answer
    1. The solubility of this product is not determined. However, various sources state that Fucoxanthin is insoluble in water but soluble in organic solvents such as ethanol; it is typically a lipid-soluble powder or oil.

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