C7493

Aminopurinyl pyranobenzopyranone monohydrate

≥98% (HPLC), solid

• Synonym(s): (5aS,7S)-7-[2-(6-Amino-3H-purin-3-yl)-1-methylethyl]-5a,6,8,9-tetrahydro-3-methyl-1H,7H-pyrano[4,3-b]benzopyran-1-one monohydrate, CP2 monohydrate
• Empirical Formula (Hill Notation): C₂₁H₂₃N₅O₃ · H₂O
• CAS Number: 603113-07-1
• Molecular Weight: 411.45
• MDL number: MFCD11045285
• UNSPSC Code: 12352200
• PubChem Substance ID: 329775077
• NACRES: NA.77

Properties

• assay: ≥98% (HPLC)
• form: solid
• solubility: DMSO: >10 mg/mL
• storage temp.: 2-8°C
• SMILES string: O.C[C@H](Cn1cnc(N)c2ncnc12)[C@H]3CCC4=CC5=C(O[C@H]4C3)C=C(C)OC5=O
• InChI: 1S/C21H23N5O3.H2O/c1-11(8-26-10-25-19(22)18-20(26)24-9-23-18)13-3-4-14-6-15-17(29-16(14)7-13)5-12(2)28-21(15)27;/h5-6,9-11,13,16H,3-4,7-8,22H2,1-2H3;1H2/t11?,13-,16-;/m0./s1
• InChI key: WIRCSRUVUSUQDQ-HTIJIITDSA-N

Description

Biochem/physiol Actions

Aminopurinyl pyranobenzopyranone monohydrate is an inhibitor of Aβ oligomer-induced cytotoxicity. It is a new Alzheimer′s research tool and potential therapeutic agent. Aminopurinyl pyranobenzopyranone monohydrate acts by inhibiting growth of Aβ oligomers and/or by preventing their toxic conformation or interaction with cellular substrates.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300
• pcodes: P264 - P301 + P310
• Hazard Classifications: Acute Tox. 2 Oral
• Storage Class: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges