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C6922

Sigma-Aldrich

Cyclohexylacetyl-Phe-Arg-Ser-Val-Gln amide

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C36H58N10O8
CAS Number:
113584-01-3
Molecular Weight:
758.91
MDL number:
MFCD00076857
UNSPSC Code:
12352200
PubChem Substance ID:
24892915

assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC(C)C(NC(=O)C(CO)NC(=O)C(CCCNC(N)=N)NC(=O)C(Cc1ccccc1)NC(=O)CC2CCCCC2)C(=O)NC(CCC(N)=O)C(N)=O

InChI

1S/C36H58N10O8/c1-21(2)30(35(54)43-24(31(38)50)15-16-28(37)48)46-34(53)27(20-47)45-32(51)25(14-9-17-41-36(39)40)44-33(52)26(18-22-10-5-3-6-11-22)42-29(49)19-23-12-7-4-8-13-23/h3,5-6,10-11,21,23-27,30,47H,4,7-9,12-20H2,1-2H3,(H2,37,48)(H2,38,50)(H,42,49)(H,43,54)(H,44,52)(H,45,51)(H,46,53)(H4,39,40,41)

Inchi Key

CQRVUZFZOUAQCT-UHFFFAOYSA-N

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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H Okunishi et al.
Advances in experimental medicine and biology, 247B, 23-28 (1989-01-01)
Kininogen sequence analogs containing amino acid residues around the Arg-Ser cleavage site of bovine kininogens were prepared with bulky aliphatic residues in P3 position. KKI-7 (containing a cyclohexylacetyl group) and KKI-8 (containing an adamantaneacetyl group) both inhibited human urinary kallikrein
The design of specific inhibitors of tissue kallikrein and their effect on the blood pressure of the rat.
J Burton et al.
Advances in experimental medicine and biology, 247B, 9-13 (1989-01-01)
P Rebuffat et al.
Histology and histopathology, 15(2), 441-444 (2000-05-16)
The effects on the pituitary-adrenocortical functions of the prolonged (7-day) blockade of endogenous bradykinin (BK) synthesis, obtained by the administration of the kallikrein inhibitor (K-I) cyclohexylacetyl-Phe-Arg-Ser-Val-Gln amide, were investigated in the rat. K-I treatment did not cause significant changes in

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