Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

C3050

Sigma-Aldrich

Cephalothin sodium salt

BioReagent, suitable for cell culture

Synonym(s):

7-(2-Thienylacetamido)cephalosporanic acid sodium salt, Cephalotin sodium salt

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C16H15N2NaO6S2
CAS Number:
Molecular Weight:
418.42
Beilstein/REAXYS Number:
4120706
EC Number:
MDL number:
UNSPSC Code:
51101500
PubChem Substance ID:

product line

BioReagent

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

water: 50 mg/mL, clear, colorless to light yellow

antibiotic activity spectrum

Gram-positive bacteria

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc3cccs3)C2=O)C([O-])=O

InChI

1S/C16H16N2O6S2.Na/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10;/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23);/q;+1/p-1/t12-,15-;/m1./s1

InChI key

VUFGUVLLDPOSBC-XRZFDKQNSA-M

Looking for similar products? Visit Product Comparison Guide

General description

Cephalotin is a first generation cephalosporin antibiotic.
Chemical structure: ß-lactam

Biochem/physiol Actions

Mode of Action: Inhibits cell wall synthesis.
Antimicrobial spectrum: Gram-positive cocci.
Mode of Resistance: Cephalosporinase production.
Mode of Action: Disrupts the synthesis of the peptidoglycan layer of bacterial cell walls.

Antimicrobial spectrum: Effective aginast both Gram-positive and Gram-negative bacteria.

Mode of Resistance: Production of cephalosporinase will inactivate the product.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Gunnar Baatrup et al.
BMC surgery, 9, 17-17 (2009-12-09)
The antibiotics used for prophylaxis during surgery may influence the rate of surgical site infections. Tetracyclines are attractive having a long half-life and few side effects when used in a single dose regimen. We studied the rate of surgical site
Esteban C Nannini et al.
Antimicrobial agents and chemotherapy, 54(5), 2206-2208 (2010-03-10)
Using 98 clinical methicillin-susceptible Staphylococcus aureus isolates of known beta-lactamase (Bla) type, we found a pronounced inoculum effect for cephalexin (mostly Bla type A and C strains), a mild inoculum effect for cephalothin (especially types B and C), and no
Eduardo Bracho-Blanchet et al.
Cirugia y cirujanos, 77(4), 279-285 (2009-11-19)
There are few randomized clinical trials that prove the effectiveness of antibiotic prophylaxis (AP) to prevent pediatric surgical site infections (SSI). We undertook this study to determine the effectiveness of AP vs. traditional scheme of antibiotics. We carried out a
Joel Veiga-Filho et al.
Annals of plastic surgery, 65(2), 144-146 (2010-06-30)
This prospective study was conducted to assess the influence of antibiotics use on surgical site infections (SSI) rates after reduction mammaplasty. Patients undergoing reduction mammaplasty were assigned to group 1 (n = 50), which received intravenous cephalotin pre- and postoperatively
Protective effect of topical antibiotics in breast augmentation.
Zhiyong Lan et al.
Plastic and reconstructive surgery, 131(1), 114e-115e (2012-12-29)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service