C1506

Cytidine 5′-triphosphate disodium salt

≥95%

• Synonym(s): CTP
• Empirical Formula (Hill Notation): C₉H₁₄N₃Na₂O₁₄P₃
• CAS Number: 36051-68-0
• Molecular Weight: 527.12
• EC Number: 252-849-3
• MDL number: MFCD00078193
• UNSPSC Code: 41106305
• PubChem Substance ID: 24892417
• NACRES: NA.77

Properties

• assay: ≥95%
• form: powder
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O
• InChI: 1S/C9H16N3O14P3.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1
• InChI key: NFQMDTRPCFJJND-WFIJOQBCSA-L

Description

General description

Cytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA.[1]

Application

Cytidine 5′-triphosphate disodium salt has been used:

• for the conversion of adenosine monophosphate (AMP) to adenosine diphosphate (ADP) in luminometry analysis[2]
• in the preparation of ribonucleotide 5′-triphosphate precursors stocks for large-scale RNA synthesis[3]
• to perform in vitro transcription[4]

Biochem/physiol Actions

Cytidine 5′-triphosphate (CTP) prevents the action of aspartate carbamoyltransferase. This enzyme participates in pyrimidine biosynthesis.[1] Like adenosine triphosphate (ATP), CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.[5]

P2X₄ purinergic receptor agonist.

Features and Benefits

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Gloves, type N95 (US)