C1376
Z-β-Ala-OH
Synonym(s):
N-Cbz-β-alanine, Z-β-alanine
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C11H13NO4
CAS Number:
Molecular Weight:
223.23
Beilstein/REAXYS Number:
1882542
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.26
Recommended Products
assay
≥98% (TLC)
form
powder
color
white
application(s)
peptide synthesis
storage temp.
2-8°C
SMILES string
OC(=O)CCNC(=O)OCc1ccccc1
InChI
1S/C11H13NO4/c13-10(14)6-7-12-11(15)16-8-9-4-2-1-3-5-9/h1-5H,6-8H2,(H,12,15)(H,13,14)
InChI key
GEVGRLPYQJTKKS-UHFFFAOYSA-N
Looking for similar products? Visit Product Comparison Guide
Application
N-Cbz-β-alanine is N-terminal Cbz protected β-alanine, homologous N-(benzyloxycarbonyl)-omega-amino acid, used in design studies for anticonvulsant drugs.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Chu-Biao Xue et al.
The Journal of organic chemistry, 67(3), 865-870 (2002-02-22)
Asymmetric syntheses of (2S,3S)-3-(tert-butoxycarbonyl)-2-piperidinecarboxylic acid (1b), (3R,4S)-4-(tert-butoxycarbonyl)-3-piperidinecarboxylic acid (2b), and their corresponding N-Boc and N-Cbz protected analogues 8a,b and 17a,b are described. Enantiomerically pure 1b has been synthesized in five steps starting from L-aspartic acid beta-tert-butyl ester. Tribenzylation of the
G K Scriba et al.
The Journal of pharmacy and pharmacology, 51(5), 549-553 (1999-07-20)
Glycine, which has weak anticonvulsant properties, has been shown to potentiate the activity of several antiepileptic drugs but not phenytoin. Recently, studies have shown that N-(benzyloxycarbonyl)glycine (Z-glycine) antagonized seizures more than glycine in addition to possessing activity in the maximal
Jiansheng Liu et al.
Biomaterials, 74, 64-76 (2015-10-09)
Despite optimal therapeutic regimen with currently available antiepileptic drugs (AEDs), approximately a third of epilepsy patients remain drug refractory. Region-specific overexpression of multidrug efflux transporters at the blood-brain barrier, such as P-glycoprotein (P-gp), might contribute to multidrug resistance (MDR) by
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
