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Key Documents

C0306

Sigma-Aldrich

7-Chlorokynurenic acid

powder

Synonym(s):

7-Chloro-4-hydroxyquinoline-2-carboxylic acid, 7-Cl-KYNA

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About This Item

Empirical Formula (Hill Notation):
C10H6ClNO3
CAS Number:
Molecular Weight:
223.61
EC Number:
MDL number:
UNSPSC Code:
12352200

form

powder

SMILES string

OC(=O)c1cc(O)c2ccc(Cl)cc2n1

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Biochem/physiol Actions

Potent NMDA glutamate receptor antagonist; antagonizes the strychnine-insensitive glycine site of the NMDA receptor.
Potent NMDA glutamate receptor antagonist; antagonizes the strychnine-insensitive glycine site of the NMDA receptor; prevents neurodegeneration produced by quinolinic acid.

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