B8685

BM 15766 sulfate

≥98% (HPLC), powder

• Synonym(s): 4-[2-[4-[3-(4-Chlorophenyl)-2-propenyl]-1-piperazinyl]ethyl]benzoic acid sulfate
• Empirical Formula (Hill Notation): C₂₂H₂₅ClN₂O₂ · H₂SO₄
• CAS Number: 86621-94-5
• Molecular Weight: 482.98
• MDL number: MFCD07370131
• UNSPSC Code: 51111800
• PubChem Substance ID: 24892089
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white
• mp: >300 °C
• solubility: DMSO: soluble 4 mg/mL; water: insoluble
• originator: Roche
• storage temp.: 2-8°C
• SMILES string: OS(O)(=O)=O.OC(=O)c1ccc(CCN2CCN(CC2)CC=Cc3ccc(Cl)cc3)cc1
• InChI: 1S/C22H25ClN2O2.H2O4S/c23-21-9-5-18(6-10-21)2-1-12-24-14-16-25(17-15-24)13-11-19-3-7-20(8-4-19)22(26)27;1-5(2,3)4/h1-10H,11-17H2,(H,26,27);(H2,1,2,3,4)
• InChI key: OVMQIVIYKXXEIT-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Dehydrocholesterol reductase inhibitor. Inhibits 7-dehydrocholesterol reductase, which catalyzes the last step of cholesterol synthesis.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves