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B1011

Sigma-Aldrich

Boc-Glu-Glu-Leu methyl ester

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C22H37N3O10
CAS Number:
72903-33-4
Molecular Weight:
503.54
MDL number:
MFCD00056255
UNSPSC Code:
12352209
PubChem Substance ID:
329773151
NACRES:
NA.26

product name

Boc-Glu-Glu-Leu methyl ester, ≥97% (HPLC)

assay

≥97% (HPLC)

form

solid

storage temp.

−20°C

SMILES string

COC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)OC(C)(C)C

InChI

1S/C22H37N3O10/c1-12(2)11-15(20(32)34-6)24-18(30)13(7-9-16(26)27)23-19(31)14(8-10-17(28)29)25-21(33)35-22(3,4)5/h12-15H,7-11H2,1-6H3,(H,23,31)(H,24,30)(H,25,33)(H,26,27)(H,28,29)/t13-,14-,15-/m0/s1

InChI key

QJKPYQOKXLMHNY-KKUMJFAQSA-N

Biochem/physiol Actions

Boc-Glu-Glu-Leu methyl ester (Boc-Glu-Glu-Leu-OMe) is an N-terminal and C-terminal blocked derivative of the tripeptide L-Glu-LGlu-L-Leu.

Substrates

Possible substrate for Vitamin K-dependent carboxylation studies.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vitamin K-dependent carboxylation.
P A Friedman et al.
The International journal of biochemistry, 19(1), 1-7 (1987-01-01)
C Vermeer et al.
Haematologia, 18(2), 71-97 (1985-01-01)
Vitamin K-dependent carboxylase is found in the liver, where it is involved in the synthesis of four blood coagulation factors and protein C. The hepatic enzyme has partly been purified and several mechanisms have been postulated for the vitamin K-dependent
R S Pottorf et al.
Journal of medicinal chemistry, 30(2), 445-448 (1987-02-01)
The synthesis of the amino acid sequence found in bovine prothrombin precursor 13-29 (PTP 13-29) has been achieved by solid-phase synthesis of the bis(acetamidomethyl)-protected linear peptide followed by cyclization to the monomeric disulfide. Synthesis of the disulfide bond was achieved

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