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A9126

Sigma-Aldrich

Adenine hemisulfate salt

≥99%

Synonym(s):

6-Aminopurine hemisulfate salt, Adenine sulfate salt

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About This Item

Linear Formula:
C5H5N5 · 1/2H2SO4
CAS Number:
321-30-2
Molecular Weight:
184.17
Beilstein/REAXYS Number:
3820263
EC Number:
206-286-5
MDL number:
MFCD00213655
UNSPSC Code:
41106305
PubChem Substance ID:
24891230
NACRES:
NA.51

biological source

synthetic (organic)

Quality Level

300

assay

≥99%

form

powder

solubility

0.5 M HCl: 10 mg/mL, clear, colorless

SMILES string

OS(O)(=O)=O.Nc1ncnc2[nH]cnc12.Nc3ncnc4[nH]cnc34

InChI

1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)

InChI key

LQXHSCOPYJCOMD-UHFFFAOYSA-N

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Application

Adenine hemisulfate salt has been used as a component of:
  • complete supplement mixture (CSM)
  • yeast extract with supplements (YES) medium for culturing S. pombe strain
  • synthetic complete glucose-based yeast media (SC) for S. cerevisiae cultures

Biochem/physiol Actions

Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors nicotinamide adenine dinucleotide (NAD), flavin adenine dinucleotide (FAD) and signaling molecules (cAMP).

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H319

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Dual-probe RNA FRET-FISH in Yeast
Wadsworth GM, et al.
Bio-protocol, 8(11) (2018)
Burak Yazgan et al.
Experimental biology and medicine (Maywood, N.J.), 246(17), 1917-1927 (2021-05-25)
Chronic kidney disease is a major global public health problem. The peptide hormones adropin and spexin modulate many physiological functions such as energy balance and glucose, lipid and protein metabolism. However, it is unclear whether these peptides may exert effects
Laurence M Brill et al.
Methods (San Diego, Calif.), 48(3), 311-319 (2009-03-11)
We describe a detailed and widely applicable method for comprehensive proteomic profiling of the fission yeast Schizosaccharomyces pombe by 2-dimensional high performance liquid chromatography-electrospray ionization-tandem mass spectrometry that demonstrates high sensitivity and robust operation. Steps ranging from the preparation of
Toshitaka Yamauchi et al.
iScience, 101477-101477 (2020-09-12)
Gut microbiota impacts the host metabolome and affects its health span. How bacterial species in the gut influence age-dependent metabolic alteration has not been elucidated. Here we show in Drosophila melanogaster that allantoin, an end product of purine metabolism, is
Olivia Ballew et al.
Current biology : CB, 29(3), 449-460 (2019-01-29)
During meiosis, diploid progenitor cells undergo one round of DNA replication followed by two rounds of chromosome segregation to form haploid gametes. Once cells initiate the meiotic divisions, it is imperative that they finish meiosis. A failure to maintain meiosis
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