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A7380

Sigma-Aldrich

L-Arginine hydroxamate hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C6H15N5O2 · HCl
CAS Number:
Molecular Weight:
225.68
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

storage temp.

−20°C

SMILES string

Cl.N[C@@H](CCCNC(N)=N)C(=O)NO

Biochem/physiol Actions

L-Arginine hydroxamate is used as a selection agent for regulatory mutants impaired in the formation of the DNA-binding protein and in which the expression of an argF::lacZ fusion is not controlled by arginine.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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S M Park et al.
Journal of bacteriology, 179(17), 5300-5308 (1997-09-01)
Gel retardation experiments indicated the presence in Pseudomonas aeruginosa cell extracts of an arginine-inducible DNA-binding protein that interacts with the control regions for the car and argF operons, encoding carbamoylphosphate synthetase and anabolic ornithine carbamoyltransferase, respectively. Both enzymes are required
M Kisumi et al.
Applied microbiology, 22(6), 987-991 (1971-12-01)
l-Arginine hydroxamate inhibited the growth of various bacteria, and the inhibition was readily reversed by arginine. l-Arginine hydroxamate (10(-3)m) completely inhibited the growth of Bacillus subtilis. This inhibitory effect was prevented by 2.5 x 10(-4)ml-arginine, which was the most effective

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