A2722

[Val⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt

≥95% (HPLC), solid

• Empirical Formula (Hill Notation): C₅₁H₈₂N₁₄O₁₈
• CAS Number: 252256-43-2
• Molecular Weight: 1179.28
• MDL number: MFCD02684499
• UNSPSC Code: 12352200
• PubChem Substance ID: 329770792

Properties

• assay: ≥95% (HPLC)
• form: solid
• UniProt accession no.: P05067
• storage temp.: −20°C
• SMILES string: CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
• InChI: 1S/C51H82N14O18/c1-25(2)39(65-45(77)32(17-19-37(69)70)59-42(74)29(53)24-66)48(80)60-30(14-9-10-20-52)44(76)64-40(26(3)4)49(81)63-35(23-38(71)72)46(78)57-27(5)41(73)58-31(16-18-36(67)68)43(75)62-34(22-28-12-7-6-8-13-28)47(79)61-33(50(82)83)15-11-21-56-51(54)55/h6-8,12-13,25-27,29-35,39-40,66H,9-11,14-24,52-53H2,1-5H3,(H,57,78)(H,58,73)(H,59,74)(H,60,80)(H,61,79)(H,62,75)(H,63,81)(H,64,76)(H,65,77)(H,67,68)(H,69,70)(H,71,72)(H,82,83)(H4,54,55,56)/t27-,29-,30-,31-,32-,33-,34-,35-,39-,40-/m0/s1
• InChI key: XVRVLVNUXPHGIL-ZSDPNEGOSA-N
• Gene Information: human ... APP(351)

Description

Amino Acid Sequence

Ser-Glu-Val-Lys-Val-Asp-Ala-Glu-Phe-Arg

Biochem/physiol Actions

β-secretase substrate corresponding to the Met/Val substitution of the amyloid precursor protein (APP) β-secretase cleavage site.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)